SCHEMBL1555

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13967	0.89	PPARG (0.39)	HTTALDH1A1KDM4EPKMPOLB
	SCHEMBL2072	0.86	ALDH1A1 (0.46)	HTTALDH1A1KDM4EMAPK1HSD17B10
	SCHEMBL1279	0.83	CYP1A2 (0.43)	HTTALDH1A1POLBMAPK1MEN1
	SCHEMBL13426	0.82	LMNA (0.42)	HTTALDH1A1POLBCACNA1FABCB1
	SCHEMBL3829	0.79	P2RX7 (0.42)	MAPTTDP1CYP1A2CYP3A4CYP2C9
	SCHEMBL8243211	0.78	ALDH1A1 (0.64)	HTTALDH1A1KDM4EPKMPOLB
	SCHEMBL18597812	0.78	CYP1A2 (0.44)	HTTALDH1A1PKMMAPK1TSHR
	SCHEMBL22257228	0.78	ALDH1A1 (0.44)	HTTALDH1A1KDM4EPKMPOLB
	SCHEMBL24042873	0.78	ALDH1A1 (0.42)	HTTALDH1A1KDM4EPKMPOLB
	SCHEMBL1683	0.77	CYP1A2 (0.43)	HTTALDH1A1POLBMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.