Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.90 |
| ▸ | MAPT | P10636 | 5/20 | 0.90 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.90 |
| ▸ | HPGD | P15428 | 5/20 | 0.82 |
| ▸ | MAOB | P27338 | 3/20 | 0.82 |
| ▸ | HTT | P42858 | 4/20 | 0.74 |
| ▸ | TP53 | P04637 | 3/20 | 0.74 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668026 | 0.96 | ALDH1A1 (0.97) | ALDH1A1MAPTHSD17B10HPGDMAOB | |
| SCHEMBL29386543 | 0.94 | ALDH1A1 (0.95) | ALDH1A1MAPTHSD17B10HPGDMAOB | |
| SCHEMBL8107900 | 0.94 | ALDH1A1 (0.95) | ALDH1A1MAPTHSD17B10HPGDMAOB | |
| SCHEMBL12123672 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10HPGDMAOB | |
| SCHEMBL12123816 | 0.81 | ALDH1A1 (0.87) | ALDH1A1MAPTHSD17B10HPGDMAOB | |
| SCHEMBL11797856 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTHSD17B10HPGDMAOB | |
| SCHEMBL14578168 | 0.79 | ACHE (0.72) | ALDH1A1MAPTHSD17B10HPGDMAOB | |
| SCHEMBL10091954 | 0.79 | HPGD (0.88) | ALDH1A1MAPTHSD17B10HPGDTP53 | |
| SCHEMBL4259988 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10HPGDTP53 | |
| SCHEMBL29773054 | 0.78 | ALDH1A1 (0.71) | ALDH1A1MAPTHSD17B10HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | claimed |
| EP-2882430-A1 | ANTIBACTERIAL INHIBITORS | McMaster University (CA) | 2015-06-17 | — | — | EP | claimed |
| WO-2014022923-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2014-02-13 | — | — | WO | claimed |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
| EP-2882430-A1 | ANTIBACTERIAL INHIBITORS | McMaster University (CA) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014022923-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MRPL21, Q6ZSR9, SPOUT1 | ALDH1A1 3080/4885MAPT 3540/4885HSD17B10 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.