Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15564219 | 0.81 | SCN5A (0.44) | SCN5ASCN9AFAAHCES1PPARG | |
| SCHEMBL15564302 | 0.81 | SCN5A (0.44) | SCN5ASCN9AFAAHCES1PPARG | |
| SCHEMBL2073780 | 0.78 | SCN5A (0.37) | SCN5ASCN9ACES1MEN1LMNA | |
| SCHEMBL15564311 | 0.75 | FAAH (0.40) | SCN5ASCN9AFAAHCES1MEN1 | |
| SCHEMBL28833568 | 0.73 | SCN5A (0.50) | SCN5ASCN9ACES1MEN1LMNA | |
| SCHEMBL5735522 | 0.70 | FAAH (0.42) | FAAHCES1S1PR4S1PR1S1PR3 | |
| SCHEMBL4740369 | 0.70 | ESR1 (0.53) | SCN5ASCN9AMEN1KMT2AGAA | |
| SCHEMBL8978824 | 0.70 | ESR1 (0.53) | SCN5ASCN9AMEN1KMT2AGAA | |
| SCHEMBL10448023 | 0.70 | ESR1 (0.53) | SCN5ASCN9AMEN1KMT2AGAA | |
| SCHEMBL5135543 | 0.70 | SCN5A (0.72) | SCN5ASCN9ACES1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882724-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS THAT ARE AMELIORATED BY INHIBITION OF HDAC | IRBM - Science Park S.p.A. (IT) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014023754-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS THAT ARE AMELIORATED BY INHIBITION OF HDAC | IRBM - SCIENCE PARK S.P.A. (IT) | 2014-02-13 | — | — | WO | disclosed |