SCHEMBL1556534

SCHEMBL1556534

CN1c2ccc(Br)c(Cl)c2N(C)c2ccc(Br)c(Cl)c21

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21848246 0.69 TTR (0.39) TDP1L3MBTL1
SCHEMBL28584478 0.68 HTR2A (0.41) TDP1L3MBTL1
SCHEMBL31058117 0.67 HTR2A (0.34)
SCHEMBL17713772 0.66 HTR2A (0.37) TDP1L3MBTL1
SCHEMBL17771808 0.63 TDP1 (0.34) TDP1L3MBTL1
SCHEMBL30126035 0.61 MYC (0.37) TDP1L3MBTL1
SCHEMBL5273045 0.60 ALDH1A1 (0.38)
SCHEMBL31057884 0.60 CDK4 (0.35)
SCHEMBL21184628 0.60 CDK4 (0.35)
SCHEMBL31735776 0.60 P2RX7 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2491013-B1 Lithium salts of pentafluorphenyl amide anions, production and use of same PHILIPPS UNIVERSITÄT MARBURG (DE) 2016-01-13 EP disclosed
US-20120245387-A1 LITHIUM SALTS OF PENTAFLUOROPHENYLAMIDE ANIONS, PREPARATION THEREOF AND USE THEREOF PHILLIPPS-UNIVERSITAT MARBURG (DE) 2012-09-27 US disclosed
EP-2491013-A1 LITHIUM SALTS OF PENTAFLUOROPHENYLAMIDE ANIONS, PREPARATION THEREOF AND USE THEREOF Philipps-Universität Marburg (DE) 2012-08-29 EP disclosed
WO-2011048152-A1 LITHIUM SALTS OF PENTAFLUOROPHENYLAMIDE ANIONS, PREPARATION THEREOF AND USE THEREOF PHILIPPS-UNIVERSITÄT MARBURG (DE) 2011-04-28 WO disclosed
EP-2314572-A1 Lithium salts of pentafluorphenyl amide anions, production and use of same PHILIPPS-UNIVERSITÄT MARBURG (DE) 2011-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120245387-A1 LITHIUM SALTS OF PENTAFLUOROPHENYLAMIDE ANIONS, PREPARATION THEREOF AND USE THEREOF TECR, SCLY, SLC7A5 TDP1 4572/4885L3MBTL1 1587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.