Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | XPNPEP2 | O43895 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | F2R | P25116 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607433 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HPGDNPC1TSHR | |
| SCHEMBL26213401 | 0.90 | PTPN1 (0.49) | ALDH1A1SMN1; SMN2HPGDNPC1TSHR | |
| SCHEMBL26724931 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDNPC1TSHR | |
| SCHEMBL26213281 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HPGDNPC1TSHR | |
| SCHEMBL25854792 | 0.83 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2XPNPEP2ACEKDM4E | |
| SCHEMBL12182476 | 0.81 | MEN1 (0.58) | ALDH1A1SMN1; SMN2HPGDNPC1TSHR | |
| SCHEMBL15607287 | 0.81 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HPGDNPC1TSHR | |
| SCHEMBL22106447 | 0.81 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HPGDNPC1TSHR | |
| SCHEMBL18731164 | 0.80 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL19104798 | 0.80 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2HPGDNPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-11-09 | — | — | US | disclosed |
| WO-2023168367-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| EP-3593648-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-2880031-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2020-06-17 | — | — | EP | disclosed |
| CN-104603132-B | Sweet taste modifier | 弗门尼舍公司 | 2020-02-21 | — | — | CN | disclosed |
| US-9745293-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9687015-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2016-11-17 | — | — | US | disclosed |
| US-9420814-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2015-12-31 | — | — | US | disclosed |
| US-9138013-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| EP-2880031-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2015-06-10 | — | — | EP | disclosed |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC | 2015-01-29 | — | — | US | disclosed |
| US-8877922-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| WO-2014025706-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | ALDH1A1 613/4885SMN1; SMN2 3389/4885HPGD 2426/4885 |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | ALDH1A1 613/4885SMN1; SMN2 3389/4885HPGD 2426/4885 |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | ALDH1A1 4236/4885SMN1; SMN2 2633/4885HPGD 905/4885 |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | CGAS, GLS2, GLS | ALDH1A1 4236/4885SMN1; SMN2 2633/4885HPGD 905/4885 |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | ALDH1A1 445/4885SMN1; SMN2 3349/4885HPGD 2313/4885 |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | ALDH1A1 445/4885SMN1; SMN2 3349/4885HPGD 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.