Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP10 | P09238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404138 | 0.85 | NTRK1 (0.46) | LMNAMAPTHTTNTRK1PRKCA | |
| SCHEMBL3406408 | 0.81 | NTRK1 (0.49) | LMNAMAPTHTTNTRK1PRKCA | |
| SCHEMBL155669 | 0.81 | NTRK1 (0.53) | LMNAMAPTHTTNTRK1PRKCA | |
| SCHEMBL155109 | 0.76 | KMT2A (0.38) | LMNANTRK1HSD17B10KMT2AKDM4E | |
| SCHEMBL155403 | 0.76 | IDO1 (0.34) | MAPTHTTNTRK1HSD17B10GLA | |
| SCHEMBL3408983 | 0.73 | KMT2A (0.38) | LMNAMAPTHTTHSD17B10GLA | |
| SCHEMBL28866215 | 0.67 | CYP1A1 (0.59) | LMNAMAPTHTTPRKCAGSK3B | |
| SCHEMBL8327395 | 0.67 | NTRK1 (0.48) | LMNAMAPTHTTNTRK1PRKCA | |
| SCHEMBL142587 | 0.67 | KMT2A (0.40) | LMNAMAPTHTTNTRK1KMT2A | |
| SCHEMBL155671 | 0.66 | MAPT (0.45) | LMNAMAPTHTTNTRK1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |