Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502110 | 0.78 | PPARG (0.36) | CASP3 | |
| SCHEMBL27527132 | 0.78 | CASP3 (0.38) | KMT2ACASP3 | |
| SCHEMBL27042592 | 0.77 | CASP3 (0.35) | KMT2ACASP3 | |
| SCHEMBL289035 | 0.77 | FABP5 (0.40) | KMT2ACASP3 | |
| SCHEMBL1557276 | 0.76 | PPARG (0.41) | KMT2ACASP3 | |
| Hydrochloric Acid SCHEMBL5505159 | 0.75 | ITGB1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL5506531 | 0.75 | ITGB1 (0.36) | — | |
| SCHEMBL4740141 | 0.74 | KMT2A (0.38) | KMT2ACASP3 | |
| SCHEMBL12466708 | 0.74 | KMT2A (0.49) | KMT2ACASP3 | |
| Hydrochloric Acid SCHEMBL5502983 | 0.73 | PPARG (0.35) | KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346871-A1 | ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER | PRISM BioLab Corporation (JP) | 2011-07-27 | — | — | EP | disclosed |
| EP-2303887-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism Biolab Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010044485-A1 | ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER | PRISM BIOLAB CORPORATION (JP) | 2010-04-22 | — | — | WO | disclosed |
| WO-2009148192-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2009-12-10 | — | — | WO | disclosed |