SCHEMBL15567002

SCHEMBL15567002

CC(C)CC(=O)N1CCCC(COc2cccc(N)c2C#N)C1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 7/20 0.45
RBP4 P02753 2/20 0.41
HCRTR1 O43613 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
RAB9A P51151 1/20 0.37
ALOX5AP P20292 1/20 0.37
FEN1 P39748 1/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CA P42336 1/20 0.36
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15568256 1.00 IRAK4 (0.45) IRAK4RBP4HCRTR1L3MBTL1HPGD
SCHEMBL15607431 1.00 IRAK4 (0.45) IRAK4RBP4HCRTR1L3MBTL1HPGD
SCHEMBL15567544 0.87 IRAK4 (0.44) IRAK4RBP4HCRTR1SMN1; SMN2NPC1
SCHEMBL15567541 0.87 IRAK4 (0.44) IRAK4RBP4HCRTR1SMN1; SMN2NPC1
SCHEMBL28358772 0.86 RBP4 (0.40) IRAK4RBP4HCRTR1
SCHEMBL22106482 0.86 IRAK4 (0.43) IRAK4RBP4HCRTR1L3MBTL1HPGD
SCHEMBL15568237 0.85 ALDH1A1 (0.43) IRAK4RBP4HCRTR1L3MBTL1HPGD
SCHEMBL15568239 0.85 ALDH1A1 (0.43) IRAK4RBP4HCRTR1L3MBTL1HPGD
SCHEMBL15607427 0.85 IRAK4 (0.41) IRAK4RBP4HCRTR1HPGDSMN1; SMN2
SCHEMBL15566996 0.85 IRAK4 (0.41) IRAK4RBP4HCRTR1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149700-A1 PROCESS FOR PREPARATION OF SULFAMOYL CHLORIDE FIRMENICH SA (CH) 2024-07-18 WO disclosed
EP-3593648-B1 SWEET FLAVOR MODIFIER FIRMENICH INCORPORATED (US) 2021-07-14 EP disclosed
EP-3593648-B1 SWEET FLAVOR MODIFIER FIRMENICH INCORPORATED (US) 2021-07-14 EP disclosed
EP-2880031-B1 SWEET FLAVOR MODIFIER FIRMENICH INCORPORATED (US) 2020-06-17 EP disclosed
EP-2880031-B1 SWEET FLAVOR MODIFIER FIRMENICH INCORPORATED (US) 2020-06-17 EP disclosed
CN-104603132-B Sweet taste modifier 弗门尼舍公司 2020-02-21 CN disclosed
US-9745293-B2 Sweet flavor modifier SENOMYX, INC. (US) 2017-08-29 US disclosed
US-9745293-B2 Sweet flavor modifier SENOMYX, INC. (US) 2017-08-29 US disclosed
US-20170183336-A1 SWEET FLAVOR MODIFIER SENOMYX, INC. 2017-06-29 US disclosed
US-20170183336-A1 SWEET FLAVOR MODIFIER SENOMYX, INC. 2017-06-29 US disclosed
US-20150374020-A1 SWEET FLAVOR MODIFIER SENOMYX, INC. 2015-12-31 US disclosed
US-9138013-B2 Sweet flavor modifier SENOMYX, INC. (US) 2015-09-22 US disclosed
US-9138013-B2 Sweet flavor modifier SENOMYX, INC. (US) 2015-09-22 US disclosed
EP-2880031-A1 SWEET FLAVOR MODIFIER Senomyx, Inc. (US) 2015-06-10 EP disclosed
US-20150031684-A1 SWEET FLAVOR MODIFIER SENOMYX, INC 2015-01-29 US disclosed
US-20150031684-A1 SWEET FLAVOR MODIFIER SENOMYX, INC 2015-01-29 US disclosed
US-8877922-B2 Sweet flavor modifier SENOMYX, INC. (US) 2014-11-04 US disclosed
US-8877922-B2 Sweet flavor modifier SENOMYX, INC. (US) 2014-11-04 US disclosed
WO-2014025706-A1 SWEET FLAVOR MODIFIER SENOMYX, INC. (US) 2014-02-13 WO disclosed
WO-2014025706-A1 SWEET FLAVOR MODIFIER SENOMYX, INC. (US) 2014-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150374020-A1 SWEET FLAVOR MODIFIER TAS2R5, TAS2R10, TAS2R50 IRAK4 1466/4885RBP4 118/4885HCRTR1 3332/4885
US-20150031684-A1 SWEET FLAVOR MODIFIER TAS2R5, TAS2R10, TAS2R50 IRAK4 1466/4885RBP4 118/4885HCRTR1 3332/4885
US-20170183336-A1 SWEET FLAVOR MODIFIER TAS2R5, TAS2R10, TAS2R50 IRAK4 1298/4885RBP4 114/4885HCRTR1 3327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.