Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20473345 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HSD17B10LMNAMAPTHTT | |
| SCHEMBL3383070 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNAMAPTHTT | |
| SCHEMBL22912542 | 0.78 | ALDH1A1 (0.37) | ALDH1A1HSD17B10LMNAMAPTHTT | |
| SCHEMBL6209988 | 0.76 | HSD17B10 (0.37) | ALDH1A1HSD17B10LMNAMAPTHTT | |
| SCHEMBL28169817 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HSD17B10LMNAMAPTHTT | |
| SCHEMBL457732 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNAMAPTALOX15 | |
| SCHEMBL3868205 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNAHTTALOX15 | |
| SCHEMBL238384 | 0.73 | — | — | |
| Water SCHEMBL10546271 | 0.72 | ALDH1A1 (0.40) | ALDH1A1HSD17B10LMNAHTTALOX15 | |
| SCHEMBL7406646 | 0.72 | ALDH1A1 (0.40) | ALDH1A1HSD17B10LMNAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617220-B2 | Method for the preparation of perfluoroalkyl containing pyrazoles carboxylates | BAYER CROPSCIENCE AG (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617220-B2 | Method for the preparation of perfluoroalkyl containing pyrazoles carboxylates | BAYER CROPSCIENCE AG (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617220-B2 | Method for the preparation of perfluoroalkyl containing pyrazoles carboxylates | BAYER CROPSCIENCE AG (DE) | 2017-04-11 | — | — | US | disclosed |
| EP-2882717-B1 | METHOD FOR THE PREPARATION OF PERFLUOROALKYL CONTAINING PYRAZOLES CARBOXYLATES | BAYER CROPSCIENCE AG (DE) | 2017-03-29 | — | — | EP | disclosed |
| EP-2882717-B1 | METHOD FOR THE PREPARATION OF PERFLUOROALKYL CONTAINING PYRAZOLES CARBOXYLATES | BAYER CROPSCIENCE AG (DE) | 2017-03-29 | — | — | EP | disclosed |
| US-20150239846-A1 | METHOD FOR THE PREPARATION OF PERFLUOROALKYL CONTAINING PYRAZOLES CARBOXYLATES | BAYER CROPSCIENCE AG (DE) | 2015-08-27 | — | — | US | disclosed |
| US-20150239846-A1 | METHOD FOR THE PREPARATION OF PERFLUOROALKYL CONTAINING PYRAZOLES CARBOXYLATES | BAYER CROPSCIENCE AG (DE) | 2015-08-27 | — | — | US | disclosed |
| US-20150239846-A1 | METHOD FOR THE PREPARATION OF PERFLUOROALKYL CONTAINING PYRAZOLES CARBOXYLATES | BAYER CROPSCIENCE AG (DE) | 2015-08-27 | — | — | US | disclosed |
| EP-2882717-A1 | METHOD FOR THE PREPARATION OF PERFLUOROALKYL CONTAINING PYRAZOLES CARBOXYLATES | Bayer CropScience AG (DE) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014023667-A1 | METHOD FOR THE PREPARATION OF PERFLUOROALKYL CONTAINING PYRAZOLES CARBOXYLATES | BAYER CROPSCIENCE AG (DE) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239846-A1 | METHOD FOR THE PREPARATION OF PERFLUOROALKYL CONTAINING PYRAZOLES CARBOXYLATES | PFAS, CYP4F3, CYP2F1 | ALDH1A1 1303/4885HSD17B10 311/4885LMNA 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.