Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20473345 | 0.89 | ALDH1A1 (0.43) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL14999139 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL22912542 | 0.81 | ALDH1A1 (0.37) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL4149915 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL28169817 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL6209988 | 0.79 | HSD17B10 (0.37) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL15567887 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL18643739 | 0.77 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28169163 | 0.77 | — | — | |
| SCHEMBL27776294 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HSD17B10LMNAALOX15MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060100430-A1 | Process for preparation of 2-alkoxy-6-(trifluoromethyl)pyrimidin-4-ol | LONZA AG (CH) | 2006-05-11 | — | — | US | claimed |
| EP-1592672-A2 | PROCESS FOR PREPARATION OF 2-ALKOXY-6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL | Lonza Ltd (CH) | 2005-11-09 | — | — | EP | claimed |
| WO-2004066905-A3 | PROCESS FOR PREPARATION OF 2-ALKOXY-6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL | LONZA AG (CH) | 2005-01-20 | — | — | WO | claimed |
| WO-2004066905-A2 | PROCESS FOR PREPARATION OF 2-ALKOXY-6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL | LONZA LTD (CH) | 2004-08-12 | — | — | WO | claimed |
| CN-1200717-A | Process for preparing 4-bromo-1,1-difluorbut-1-ene and 2,4-dibromo-1,1,1-trifluorobutane | ZENECA LTD (GB) | 1998-12-02 | — | — | CN | claimed |
| EP-0850211-A1 | PROCESS FOR THE PREPARATION OF 4-BROMO-1,1-DIFLUOROBUT-1-ENE AND 2,4-DIBROMO-1,1,1-TRIFLUOROBUTANE | ZENECA LIMITED (GB) | 1998-07-01 | — | — | EP | claimed |
| WO-1997009292-A1 | PROCESS FOR THE PREPARATION OF 4-BROMO-1,1-DIFLUOROBUT-1-ENE AND 2,4-DIBROMO-1,1,1-TRIFLUOROBUTANE | ZENECA LIMITED (GB) | 1997-03-13 | — | — | WO | claimed |
| WO-2024178967-A1 | NON-CHEMICALLY AMPLIFIED COUMARIN PHOTORESISTS SUITABLE FOR PERFORMING PHOTOETCHING AT VARIOUS WAVELENGTHS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院理化技术研究所 | 2024-09-06 | — | — | WO | disclosed |
| US-11702396-B2 | Hydrophobic compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| EP-4021441-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | Trustees of Dartmouth College (US) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021042046-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2021-03-04 | — | — | WO | disclosed |
| CN-110437146-A | A kind of preparation of quinoline 4- hydroxy methacrylates class compound and its application in controlling plant diseases | UNIV LANZHOU | 2019-11-12 | — | — | CN | disclosed |
| CN-104829605-B | 1 substitution 5 trifluoromethyl 4 pyrazoles joins 1,3,4 oxadiazole thioethers or sulfone derivatives and its application | 贵州大学 | 2018-03-23 | — | — | CN | disclosed |
| US-5693646-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |
| US-5693647-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |
| US-5688808-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-11-18 | — | — | US | disclosed |
| US-5688810-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0800519-A1 | STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1997009292-A1 | PROCESS FOR THE PREPARATION OF 4-BROMO-1,1-DIFLUOROBUT-1-ENE AND 2,4-DIBROMO-1,1,1-TRIFLUOROBUTANE | ZENECA LIMITED (GB) | 1997-03-13 | — | — | WO | disclosed |
| WO-1996019458-A2 | STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1996-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702396-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | ALDH1A1 1851/4885HSD17B10 647/4885LMNA 2186/4885 |
| US-20060100430-A1 | Process for preparation of 2-alkoxy-6-(trifluoromethyl)pyrimidin-4-ol | CLCN2, CLIC1, CLIC4 | ALDH1A1 436/4885HSD17B10 2841/4885LMNA 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.