SCHEMBL15567982

SCHEMBL15567982

O=C(O)Oc1cccnc1-c1cccc(-c2ccc(Cl)cc2)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 3/20 0.45
L3MBTL1 Q9Y468 3/20 0.43
GAA P10253 2/20 0.43
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CTRC Q99895 2/20 0.41
MAP4K4 O95819 1/20 0.39
PDE4A P27815 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
CNR1 P21554 1/20 0.39
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
HPGD P15428 1/20 0.37
CNR2 P34972 2/20 0.37
TRPV1 Q8NER1 1/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15567980 0.80 KDM4E (0.54) KMOL3MBTL1LMNASMN1; SMN2CTRC
SCHEMBL17201767 0.79 KDM4E (0.53) KMOL3MBTL1LMNASMN1; SMN2CTRC
Potassium SCHEMBL17201770 0.79 KDM4E (0.53) KMOL3MBTL1LMNASMN1; SMN2CTRC
SCHEMBL15569111 0.76 NPC1 (0.55) KMOL3MBTL1LMNASMN1; SMN2CNR1
Potassium Ion SCHEMBL17201768 0.75 KMO (0.43) KMOL3MBTL1GAASMN1; SMN2CTRC
SCHEMBL5702580 0.75 KDM4E (0.50) L3MBTL1GAALMNASMN1; SMN2KDM4E
SCHEMBL6550571 0.70 RAB9A (0.59) KMOL3MBTL1GAALMNASMN1; SMN2
SCHEMBL15467341 0.69 ASIC3 (0.41) KMOL3MBTL1LMNACNR1KDM4E
SCHEMBL17201766 0.69 KDM4E (0.58) KMOL3MBTL1LMNASMN1; SMN2CTRC
SCHEMBL5178813 0.69 SMN1; SMN2 (0.53) L3MBTL1GAALMNASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2882732-B1 HERBICIDALLY ACTIVE DERIVATIVES OF 6'-PHENYL-2,2'-BIPYRIDIN-3-CARBOXYLIC ACID BAYER CROPSCIENCE AG (DE) 2017-04-12 EP disclosed
EP-2882732-A1 HERBICIDALLY ACTIVE 6'-PHENYL-2,2'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES Bayer CropScience AG (DE) 2015-06-17 EP disclosed
WO-2014023670-A1 HERBICIDALLY ACTIVE 6'-PHENYL-2,2'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2014-02-13 WO disclosed