Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.58 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.58 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.58 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15567214 | 0.87 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTMEN1CYP1A2 | |
| SCHEMBL15568555 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTMEN1CYP1A2 | |
| SCHEMBL15568517 | 0.84 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL15568343 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTMEN1CYP1A2 | |
| SCHEMBL3596348 | 0.81 | FAAH (1.00) | FAAHKDM4EMAPTCA12CA2 | |
| SCHEMBL15568741 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL15568468 | 0.78 | MEN1 (0.74) | ALDH1A1MAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL15685964 | 0.78 | ADRB1 (0.61) | ALDH1A1MAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL15568337 | 0.77 | CYP1A2 (0.97) | ALDH1A1MAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL15568462 | 0.77 | CYP1A2 (0.75) | FAAHMAPTMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014027053-A1 | BENZIMIDAZOLES FOR THE TREATMENT OF CANCER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-02-20 | — | — | WO | claimed |
| WO-2014027053-A1 | BENZIMIDAZOLES FOR THE TREATMENT OF CANCER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-02-20 | — | — | WO | disclosed |