Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 7/20 | 0.44 |
| ▸ | PDE1A | P54750 | 2/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436390 | 1.00 | KDM4E (0.45) | KDM4EMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL996651 | 0.83 | KDM4E (0.41) | KDM4EMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL24010300 | 0.81 | KDM4E (0.40) | KDM4EMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL4369695 | 0.81 | PDE4B (0.67) | PDE4BPDE1BPDE4D | |
| SCHEMBL10787135 | 0.79 | ALDH1A1 (0.45) | KDM4EMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL28446875 | 0.79 | MEN1 (0.45) | KDM4EMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL4379192 | 0.77 | PDE4B (0.60) | KDM4EALDH1A1HSD17B10PDE4BPDE1B | |
| SCHEMBL2178344 | 0.77 | HTR1A (0.59) | KDM4EMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL26400701 | 0.77 | PDE1B (0.45) | KDM4EMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL22501504 | 0.76 | KMT2A (0.60) | KDM4EMEN1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
| CN-102066368-A | 1,2-benzisothiazole compounds useful for combating animal pests | BASF SE | 2011-05-18 | — | — | CN | disclosed |
| EP-2303874-A2 | SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2011-04-06 | — | — | EP | disclosed |
| EP-2069306-B1 | QUINOLINYLMETHYL COMPOUNDS | BASF SE (DE) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009153285-A2 | SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2009-12-23 | — | — | WO | disclosed |
| US-20090280982-A1 | Quinolinylmethyl Compounds | BASF SE (DE) | 2009-11-12 | — | — | US | disclosed |
| CN-101516851-A | Quinolinylmethyl compounds | BASF AG (DE) | 2009-08-26 | — | — | CN | disclosed |
| EP-2069306-A1 | QUINOLINYLMETHYL COMPOUNDS | BASF SE (DE) | 2009-06-17 | — | — | EP | disclosed |
| CN-101443313-A | Quinoline derivatives and their use as pesticides | BASF SE (DE) | 2009-05-27 | — | — | CN | disclosed |
| US-20090029855-A1 | Quinoline Derivatives and Their Use as Pesticides | BASF SE (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-2007727-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | BASF SE (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2008031824-A1 | QUINOLINYLMETHYL COMPOUNDS | BASF SE (DE) | 2008-03-20 | — | — | WO | disclosed |
| WO-2007104726-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | BASF SE (DE) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280982-A1 | Quinolinylmethyl Compounds | CBR3, C1S, C5 | KDM4E 1573/4885MEN1 2807/4885ALDH1A1 1812/4885 |
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | GLRX3, CBR3, PRDX1 | KDM4E 4261/4885MEN1 3287/4885ALDH1A1 2095/4885 |
| US-20090029855-A1 | Quinoline Derivatives and Their Use as Pesticides | CBR3, HCRTR1, HCAR3 | KDM4E 4207/4885MEN1 2744/4885ALDH1A1 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.