Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CASP9 | P55211 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15570276 | 0.83 | KDM4E (0.41) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15570041 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15569660 | 0.73 | KDM5B (0.42) | POLBMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL15569366 | 0.72 | MAPT (0.31) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL31467465 | 0.72 | HCAR2 (0.43) | KDM4EALDH1A1NPC1HCAR2ALOX15 | |
| SCHEMBL387508 | 0.70 | ERCC1 (0.37) | POLBMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL387706 | 0.70 | HCAR2 (0.40) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4594309 | 0.69 | ALDH1A1 (0.40) | POLBMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL17224164 | 0.68 | RAB9A (0.40) | POLBMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10357492 | 0.68 | HCAR2 (0.33) | POLBMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014031971-A1 | HERBICIDAL PYRIDAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-27 | — | — | WO | disclosed |