SCHEMBL15570864

SCHEMBL15570864

O=C(O)c1cccc(C(=O)ON2CCOCC2)c1.[NaH]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.56
KMT2A Q03164 5/20 0.50
MAPT P10636 3/20 0.50
RAB9A P51151 2/20 0.50
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NPC1 O15118 2/20 0.44
MEN1 O00255 2/20 0.44
PRKDC P78527 1/20 0.44
PIK3CA P42336 1/20 0.43
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
POLB P06746 2/20 0.42
APAF1 O14727 1/20 0.42
CASP3 P42574 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15572814 0.97 KMO (0.56) KMOKMT2AMAPTRAB9ALMNA
SCHEMBL15571628 0.97 KMO (0.56) KMOKMT2AMAPTRAB9ALMNA
SCHEMBL15572991 0.97 KMO (0.56) KMOKMT2AMAPTRAB9ALMNA
SCHEMBL27442186 0.85 LMNA (0.57) KMT2AMAPTRAB9ALMNASMN1; SMN2
SCHEMBL15571800 0.85 GAA (0.51) KMOKMT2AMAPTRAB9ASMN1; SMN2
SCHEMBL226315 0.84 KMT2A (0.55) KMT2AMAPTLMNASMN1; SMN2NPC1
SCHEMBL5893722 0.84 NPC1 (0.46) KMOKMT2AMAPTRAB9ALMNA
Ammonia Solution, Strong SCHEMBL11880905 0.83 KMT2A (0.54) KMT2AMAPTLMNASMN1; SMN2NPC1
SCHEMBL15571345 0.82 ALDH1A1 (0.51) KMOKMT2AMAPTRAB9ASMN1; SMN2
SCHEMBL15571508 0.82 GAA (0.51) KMOKMT2AMAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150238948-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS Midori Renewables, Inc. (US) 2015-08-27 US disclosed
EP-2888043-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS Midori Renewables, Inc. (US) 2015-07-01 EP disclosed
WO-2014032004-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS Midori Renewables, Inc. (US) 2014-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150238948-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS LCT, AGL, MGAM KMO 605/4885KMT2A 571/4885MAPT 2685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.