Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | PPIG | Q13427 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPRB | P23467 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577125 | 1.00 | BLM (0.40) | BLMFDPSSMN1; SMN2HIF1APPIB | |
| SCHEMBL12141665 | 0.86 | ALDH1A1 (0.47) | FDPSSMN1; SMN2HIF1ACYP3A4CYP1A2 | |
| SCHEMBL20347416 | 0.78 | BLM (0.45) | BLMFDPSSMN1; SMN2HIF1APPIB | |
| SCHEMBL934104 | 0.77 | SMN1; SMN2 (0.52) | FDPSSMN1; SMN2HIF1ACYP3A4CYP1A2 | |
| SCHEMBL20333729 | 0.77 | ITGB1 (0.40) | BLMFDPSSMN1; SMN2HIF1APPIB | |
| SCHEMBL20350718 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2HIF1ACYP1A2PTPRBALDH1A1 | |
| SCHEMBL20333381 | 0.76 | RXRA (0.39) | BLMSMN1; SMN2HIF1ACYP3A4LMNA | |
| SCHEMBL20333384 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2PPIDCYP3A4CYP1A2LMNA | |
| SCHEMBL20333769 | 0.73 | FFAR1 (0.50) | LMNA | |
| SCHEMBL19953750 | 0.72 | PTPN1 (0.42) | EPHX2PTPN1PTPRBPTPN2PTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897603-A1 | METHODS OF INHIBITING HAIR GROWTH | Nogra Pharma Limited (IE) | 2015-07-29 | — | — | EP | claimed |
| WO-2014041141-A1 | METHODS OF INHIBITING HAIR GROWTH | NOGRA PHARMA LIMITED (IE) | 2014-03-20 | — | — | WO | claimed |
| WO-2017046343-A1 | COMPOSITIONS FOR RECTAL ADMINISTRATION IN THE TREATMENT OF ULCERATIVE COLITIS AND METHODS OF USING SAME | NOGRA PHARMA LIMITED (IE) | 2017-03-23 | — | — | WO | disclosed |