SCHEMBL15577333

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15577395	0.91	ALDH1A1 (0.46)	HTTSMN1; SMN2HSD17B10AHRRAB9A
	SCHEMBL15577617	0.88	SLC6A3 (0.45)	MAP4K1
	SCHEMBL15577335	0.88	MAPT (0.49)	SMN1; SMN2HSD17B10RAB9AMAPTHCRTR2
	SCHEMBL18549334	0.87	ALDH1A1 (0.40)	HTTGAALMNAKDM4ETDP1
	SCHEMBL15605982	0.85	MAP4K1 (0.44)	MAP4K1
	SCHEMBL15577507	0.85	ROCK2 (0.41)	SMN1; SMN2RAB9AMAPTMAP4K1
	SCHEMBL15579321	0.81	MAP4K1 (0.37)	HTTMAP4K1
	SCHEMBL20686266	0.81	MAP4K1 (0.36)	HTTMAPTGAALMNAKDM4E
	SCHEMBL15579146	0.80	GAA (0.50)	HTTSMN1; SMN2HSD17B10AHRRAB9A
	SCHEMBL15577412	0.79	ABL1 (0.47)	SMN1; SMN2RAB9AMAPTLMNAMAP4K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.