Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16694093 | 0.90 | — | — | |
| SCHEMBL16694641 | 0.90 | — | — | |
| SCHEMBL16694288 | 0.88 | — | — | |
| SCHEMBL15599155 | 0.82 | ACHE (0.74) | ACHE | |
| SCHEMBL15598860 | 0.79 | HSP90AA1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL16874203 | 0.78 | HSP90AA1 (0.36) | — | |
| SCHEMBL16694487 | 0.78 | ACHE (0.70) | ACHE | |
| SCHEMBL16694155 | 0.78 | ACHE (0.52) | ACHE | |
| SCHEMBL15598856 | 0.76 | GPR119 (0.46) | — | |
| SCHEMBL15598886 | 0.76 | ACHE (0.52) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2871184-B1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2017-09-06 | — | — | EP | claimed |
| US-20150191480-A1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2015-07-09 | — | — | US | claimed |
| EP-2871184-A1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2015-05-13 | — | — | EP | claimed |
| EP-2871184-B1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2017-09-06 | — | — | EP | disclosed |
| EP-2871184-B1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2017-09-06 | — | — | EP | disclosed |
| US-9346818-B2 | Benzodioxole derivative and preparation method and use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2016-05-24 | — | — | US | disclosed |
| US-9346818-B2 | Benzodioxole derivative and preparation method and use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2016-05-24 | — | — | US | disclosed |
| US-9346818-B2 | Benzodioxole derivative and preparation method and use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2016-05-24 | — | — | US | disclosed |
| US-20150191480-A1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2015-07-09 | — | — | US | disclosed |
| US-20150191480-A1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2015-07-09 | — | — | US | disclosed |
| US-20150191480-A1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2015-07-09 | — | — | US | disclosed |
| EP-2871184-A1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2015-05-13 | — | — | EP | disclosed |
| EP-2871184-A1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2015-05-13 | — | — | EP | disclosed |
| WO-2014005421-A1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | 浙江海正药业股份有限公司 (CN) | 2014-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191480-A1 | BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | ACHE, BCHE, BBOX1 | ACHE 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.