SCHEMBL16694487

SCHEMBL16694487

O=C1c2cc3c(cc2CN1CCC1CCN(Cc2ccccc2)CC1)OCO3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15599166 0.90 ACHE (0.56) ACHE
SCHEMBL15599162 0.89 ACHE (0.56) ACHE
SCHEMBL15599180 0.88 ACHE (0.67) ACHE
SCHEMBL19316117 0.88 ACHE (0.67) ACHE
SCHEMBL15599181 0.87 ACHE (0.53) ACHE
SCHEMBL15599155 0.84 ACHE (0.74) ACHE
SCHEMBL19316116 0.83 ACHE (0.61) ACHE
SCHEMBL15599165 0.82 ACHE (0.43) ACHE
SCHEMBL15599156 0.78 ITGB3 (0.50)
SCHEMBL15599090 0.78 ACHE (0.53) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2871184-B1 BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF ZHEJIANG HISUN PHARM CO LTD (CN) 2017-09-06 EP claimed
US-20150191480-A1 BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2015-07-09 US claimed
EP-2871184-A1 BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) 2015-05-13 EP claimed
EP-2871184-B1 BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF ZHEJIANG HISUN PHARM CO LTD (CN) 2017-09-06 EP disclosed
US-9346818-B2 Benzodioxole derivative and preparation method and use thereof ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2016-05-24 US disclosed
US-9346818-B2 Benzodioxole derivative and preparation method and use thereof ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2016-05-24 US disclosed
US-9346818-B2 Benzodioxole derivative and preparation method and use thereof ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2016-05-24 US disclosed
US-20150191480-A1 BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2015-07-09 US disclosed
US-20150191480-A1 BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2015-07-09 US disclosed
US-20150191480-A1 BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2015-07-09 US disclosed
EP-2871184-A1 BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) 2015-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191480-A1 BENZODIOXOLE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF ACHE, BCHE, BBOX1 ACHE 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.