SCHEMBL15599154

SCHEMBL15599154

Cc1ccc(OC(C)C(=O)O)cc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.74
CYP1A2 P05177 1/20 0.54
GAA P10253 1/20 0.54
CYP2C9 P11712 1/20 0.54
PKM P14618 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 4/20 0.52
HPGD P15428 4/20 0.52
KDM4E B2RXH2 3/20 0.52
TSHR P16473 1/20 0.49
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
HTR2B P41595 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.46
ALDH2 P05091 1/20 0.45
TRPA1 O75762 1/20 0.44
PTGS1 P23219 1/20 0.44
CACNA1C Q13936 1/20 0.44
PPARG P37231 2/20 0.43
PPARA Q07869 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13220460 0.86 TDP1 (0.54) TDP1CYP1A2GAACYP2C9PKM
SCHEMBL8406823 0.85 TDP1 (1.00) TDP1CYP1A2GAACYP2C9PKM
SCHEMBL13211785 0.83 ALDH2 (0.55) TDP1GAAALDH1A1HPGDKDM4E
SCHEMBL22542311 0.81 LMNA (0.57) TDP1ALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL4237202 0.81 TRPA1 (0.50) TDP1ALDH1A1HPGDKDM4ETSHR
SCHEMBL502837 0.81 CYP1A2 (0.67) TDP1CYP1A2GAACYP2C9PKM
SCHEMBL3848321 0.81 CYP1A2 (0.67) TDP1CYP1A2GAACYP2C9PKM
SCHEMBL637870 0.81 CYP1A2 (0.67) TDP1CYP1A2GAACYP2C9PKM
SCHEMBL14447012 0.81 TDP1 (0.72) TDP1CYP1A2GAACYP2C9PKM
SCHEMBL13336923 0.81 TDP1 (0.72) TDP1CYP1A2GAACYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2866898-B1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER INC (US) 2018-04-04 EP disclosed
US-9469725-B2 Ultraviolet radiation absorbing polymers JOHNSON & JOHNSON CONSUMER INC. (US) 2016-10-18 US disclosed
WO-2014004176-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO disclosed