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Sugi Predict / Compounds / SCHEMBL1560107

SCHEMBL1560107

SCHEMBL1560107

Cc1cc(C)c2cccc(C(O)c3c(Cl)ccc(S(=O)(=O)C(CC(N)=O)(NC(=O)c4ccc(C(N)=O)cc4)N4CCCC4C(=O)O)c3Cl)c2n1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ BDKRB2 P30411 9/20 0.42
▸ RORC P51449 11/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2638880 0.79 RORC (0.55) BDKRB2RORC
SCHEMBL1772541 0.72 BDKRB2 (0.54) BDKRB2RORC
SCHEMBL7814524 0.66 BDKRB2 (0.47) BDKRB2RORC
SCHEMBL4592164 0.64 RORC (0.47) BDKRB2RORC
SCHEMBL2638878 0.63 RORC (0.56) BDKRB2RORC
SCHEMBL6946090 0.62 RORC (0.83) BDKRB2RORC
SCHEMBL3743960 0.62 RORC (0.83) BDKRB2RORC
SCHEMBL16982328 0.61 BDKRB2 (0.76) BDKRB2
SCHEMBL8181772 0.61 RORC (0.71) BDKRB2RORC
SCHEMBL2344304 0.60 BDKRB2 (0.75) BDKRB2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2303268-A1 PHARMACEUTICAL COMPOSITIONS BASED ON KININ B2 RECEPTOR ANTAGONISTS AND CORTICOSTEROIDS, AND THEIR USE Istituto Luso Farmaco d'Italia S.p.A. (IT) 2011-04-06 — — EP claimed