Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15524913 | 0.94 | ALOX5 (0.59) | MAPTHDAC6ALOX5EPHX2KCNT1 | |
| SCHEMBL17154059 | 0.91 | ALOX5 (0.52) | MAPTHDAC6HDAC1ALOX5EPHX2 | |
| SCHEMBL15526096 | 0.91 | ALOX5 (0.52) | HDAC6HDAC1ALOX5EPHX2KCNT1 | |
| SCHEMBL22771522 | 0.90 | HDAC6 (0.53) | MAPTHDAC6HDAC1ALOX5EPHX2 | |
| SCHEMBL15601416 | 0.90 | ALOX5 (0.53) | HDAC6HDAC1ALOX5EPHX2KCNT1 | |
| SCHEMBL15601465 | 0.90 | ALOX5 (0.52) | MAPTHDAC6HDAC1ALOX5EPHX2 | |
| SCHEMBL17154044 | 0.89 | ALOX5 (0.52) | HDAC6HDAC1ALOX5EPHX2KCNT1 | |
| SCHEMBL15601491 | 0.88 | HDAC6 (0.52) | MAPTHDAC6HDAC1ALOX5EPHX2 | |
| SCHEMBL21237727 | 0.87 | ALOX5 (0.51) | MAPTHDAC6HDAC1ALOX5EPHX2 | |
| SCHEMBL17702506 | 0.86 | ALOX5 (0.49) | HDAC6HDAC1ALOX5EPHX2KCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321750-B2 | ROR modulators and their uses | INNOV17 LLC (US) | 2016-04-26 | — | — | US | disclosed |
| US-9321750-B2 | ROR modulators and their uses | INNOV17 LLC (US) | 2016-04-26 | — | — | US | disclosed |
| US-20150284366-A1 | ROR MODULATORS AND THEIR USES | INNOV17 LLC | 2015-10-08 | — | — | US | disclosed |
| US-20150284366-A1 | ROR MODULATORS AND THEIR USES | INNOV17 LLC | 2015-10-08 | — | — | US | disclosed |
| WO-2013159095-A1 | ROR MODULATORS AND THEIR USES | GAWECO ANDERSON (US) | 2013-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284366-A1 | ROR MODULATORS AND THEIR USES | RORA, RORB, RORC | MAPT 2512/4885HDAC6 501/4885HDAC1 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.