Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isovanillic Acid Methyl Ester SCHEMBL1560813 | 0.91 | LPAR1 (0.49) | LPAR1ACHEPOLBP4HBHDAC1 | |
| SCHEMBL1990286 | 0.90 | LPAR1 (0.51) | LPAR1ACHEPOLBSIRT2MEN1 | |
| Isovanillic Acid Methyl Ester SCHEMBL1561708 | 0.88 | LPAR1 (0.46) | LPAR1ACHEPOLBSCDMEN1 | |
| SCHEMBL1560333 | 0.85 | LPAR1 (0.64) | LPAR1ACHEPOLBHDAC1HDAC2 | |
| SCHEMBL1988472 | 0.80 | LPAR1 (0.49) | LPAR1ACHEPOLBHDAC1HDAC2 | |
| Isovanillic Acid Methyl Ester SCHEMBL1561379 | 0.78 | P4HB (0.47) | LPAR1P4HBHDAC1HDAC2SIRT2 | |
| SCHEMBL1989114 | 0.77 | LMNA (0.48) | LPAR1POLBMEN1KMT2AMAPT | |
| SCHEMBL17844325 | 0.74 | HPGD (0.57) | MAPTALDH1A1 | |
| SCHEMBL1561673 | 0.73 | LPAR1 (0.56) | LPAR1ACHEPOLBHDAC1HDAC2 | |
| SCHEMBL17844306 | 0.72 | NPC1 (0.59) | HDAC1MEN1KMT2AHSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-A1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | Sanofi-aventis (FR) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009135590-A1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2009-11-12 | — | — | WO | disclosed |