Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989114 | 0.91 | LMNA (0.48) | LPAR1LMNAG6PDCRHBPCRHR2 | |
| Isovanillic Acid Methyl Ester SCHEMBL1560433 | 0.88 | LPAR1 (0.50) | LPAR1MEN1MAPTKMT2AACHE | |
| Isovanillic Acid Methyl Ester SCHEMBL1560813 | 0.86 | LPAR1 (0.49) | LPAR1MEN1KMT2AACHESCD | |
| SCHEMBL1560333 | 0.80 | LPAR1 (0.64) | LPAR1LMNAMEN1MAPTKMT2A | |
| SCHEMBL25039485 | 0.78 | ALDH1A1 (0.47) | LMNAMEN1MAPTKMT2ANPC1 | |
| SCHEMBL29729342 | 0.78 | ALDH1A1 (0.47) | LMNAMEN1MAPTKMT2ANPC1 | |
| SCHEMBL1990286 | 0.77 | LPAR1 (0.51) | LPAR1LMNAMEN1MAPTKMT2A | |
| SCHEMBL1988472 | 0.76 | LPAR1 (0.49) | LPAR1LMNAMEN1MAPTKMT2A | |
| Isovanillic Acid Methyl Ester SCHEMBL1561379 | 0.74 | P4HB (0.47) | LPAR1MAPT | |
| SCHEMBL1561309 | 0.74 | LPAR1 (0.55) | LPAR1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-A1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | Sanofi-aventis (FR) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009135590-A1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2009-11-12 | — | — | WO | disclosed |