SCHEMBL15612295

SCHEMBL15612295

CO[Si](CCOCCN(C)C)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
USP2 O75604 1/20 0.33
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
HTR7 P34969 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRM3 P20309 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15611470 0.87 ALDH1A1 (0.35)
SCHEMBL15612758 0.87 CA12 (0.36) CA12CA1CA2CA9USP2
SCHEMBL6138643 0.83 LMNA (0.33)
SCHEMBL15612475 0.80 CA12 (0.37) CA12CA1CA2CA9USP2
SCHEMBL15612038 0.79
SCHEMBL29155521 0.79 CA12 (0.35) CA12CA1CA2CA9USP2
SCHEMBL15611857 0.78 CA12 (0.36) CA12CA1CA2CA9USP2
SCHEMBL15970143 0.78
SCHEMBL15611887 0.78 ALDH1A1 (0.35)
SCHEMBL15611769 0.78 MEN1 (0.44) CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9249276-B2 Conjugated diene polymer end-modified with alkoxysilane derivative KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-02 US claimed
US-20140243447-A1 CONJUGATED DIENE POLYMER END-MODIFIED WITH ALKOXYSILANE DERIVATIVE KOREAN KUMHO PETROCHEMICAL CO., LTD. (KR) 2014-08-28 US claimed
US-20140088320-A1 ALKYLALKOXYSILANE COMPOUNDS CONTAINING ETHER GROUP AND DIALKYLAMINO GROUP AND PROCESS FOR PREPARING THE COMPOUNDS KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2014-03-27 US claimed
US-9434751-B2 Alkylalkoxysilane compounds containing ether group and dialkylamino group and process for preparing the compounds KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-09-06 US disclosed
US-9249276-B2 Conjugated diene polymer end-modified with alkoxysilane derivative KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-02 US disclosed
US-20140243447-A1 CONJUGATED DIENE POLYMER END-MODIFIED WITH ALKOXYSILANE DERIVATIVE KOREAN KUMHO PETROCHEMICAL CO., LTD. (KR) 2014-08-28 US disclosed
US-20140088320-A1 ALKYLALKOXYSILANE COMPOUNDS CONTAINING ETHER GROUP AND DIALKYLAMINO GROUP AND PROCESS FOR PREPARING THE COMPOUNDS KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2014-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140088320-A1 ALKYLALKOXYSILANE COMPOUNDS CONTAINING ETHER GROUP AND DIALKYLAMINO GROUP AND PROCESS FOR PREPARING THE COMPOUNDS ALKBH3, ALKBH2, AGPS CA12 2602/4885CA1 3336/4885CA2 3564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.