Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 17/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 12/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30563666 | 0.77 | KDM4E (0.39) | S1PR3S1PR4S1PR2KDM4EALDH1A1 | |
| SCHEMBL595295 | 0.77 | KDM4E (0.39) | S1PR3S1PR4S1PR2KDM4EALDH1A1 | |
| SCHEMBL15612244 | 0.77 | S1PR3 (0.36) | S1PR3S1PR1S1PR4S1PR2KDM4E | |
| SCHEMBL20209121 | 0.77 | ADRA2A (0.35) | S1PR3S1PR1S1PR4S1PR2KDM4E | |
| SCHEMBL26713519 | 0.74 | KDM4E (0.36) | S1PR3S1PR4S1PR2KDM4EALDH1A1 | |
| SCHEMBL13316533 | 0.73 | GBA1 (0.40) | S1PR3S1PR1S1PR4S1PR2GBA1 | |
| SCHEMBL14811134 | 0.71 | KDM4E (0.42) | S1PR3S1PR1S1PR4S1PR2KDM4E | |
| SCHEMBL15955034 | 0.71 | KDM4E (0.42) | S1PR3S1PR1S1PR4S1PR2KDM4E | |
| SCHEMBL27936113 | 0.70 | GBA1 (0.38) | S1PR3S1PR1S1PR4S1PR2KDM4E | |
| SCHEMBL20525062 | 0.70 | GBA1 (0.33) | S1PR3S1PR4KDM4EALDH1A1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206126-B2 | Phenicol antibacterial agents | ZOETIS SERVICES LLC (US) | 2015-12-08 | — | — | US | disclosed |
| US-9206126-B2 | Phenicol antibacterial agents | ZOETIS SERVICES LLC (US) | 2015-12-08 | — | — | US | disclosed |
| US-9206126-B2 | Phenicol antibacterial agents | ZOETIS SERVICES LLC (US) | 2015-12-08 | — | — | US | disclosed |
| EP-2900641-A1 | PHENICOL ANTIBACTERIAL AGENTS | Zoetis LLC (US) | 2015-08-05 | — | — | EP | disclosed |
| US-20140088046-A1 | PHENICOL ANTIBACTERIAL AGENTS | ZOETIS LLC (US) | 2014-03-27 | — | — | US | disclosed |
| US-20140088046-A1 | PHENICOL ANTIBACTERIAL AGENTS | ZOETIS LLC (US) | 2014-03-27 | — | — | US | disclosed |
| US-20140088046-A1 | PHENICOL ANTIBACTERIAL AGENTS | ZOETIS LLC (US) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088046-A1 | PHENICOL ANTIBACTERIAL AGENTS | MRPL21, CLPP, CLPX | S1PR3 3476/4885S1PR1 3845/4885S1PR4 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.