SCHEMBL595295

SCHEMBL595295

FC(F)c1ccc(Br)cn1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
S1PR3 Q99500 9/20 0.37
S1PR4 O95977 4/20 0.37
ADRA2A P08913 2/20 0.36
ADRA2B P18089 2/20 0.36
ADRA2C P18825 2/20 0.36
PLAU P00749 1/20 0.36
GBA1 P04062 1/20 0.36
FDPS P14324 1/20 0.35
S1PR2 O95136 2/20 0.33
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30563666 1.00 KDM4E (0.39) KDM4EALDH1A1S1PR3S1PR4ADRA2A
SCHEMBL14811134 0.79 KDM4E (0.42) KDM4EALDH1A1S1PR3S1PR4ADRA2A
SCHEMBL15955034 0.79 KDM4E (0.42) KDM4EALDH1A1S1PR3S1PR4ADRA2A
SCHEMBL5254866 0.78 KDM4E (0.40) KDM4EALDH1A1S1PR3S1PR4ADRA2A
SCHEMBL15612596 0.77 S1PR3 (0.34) KDM4EALDH1A1S1PR3S1PR4ADRA2A
SCHEMBL681840 0.76 GBA1 (0.41) KDM4EALDH1A1S1PR3S1PR4ADRA2A
SCHEMBL7263792 0.74 S1PR3 (0.40) KDM4EALDH1A1S1PR3S1PR4ADRA2A
SCHEMBL31473349 0.74 S1PR3 (0.35) KDM4EALDH1A1S1PR3S1PR4S1PR2
SCHEMBL20525062 0.74 GBA1 (0.33) KDM4EALDH1A1S1PR3S1PR4ADRA2A
SCHEMBL20361485 0.74 GBA1 (0.37) KDM4EALDH1A1S1PR3S1PR4ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132139-A1 HIV INHIBITOR COMPOUNDS GILEAD SCIENCES INC (US) 2026-05-14 US disclosed
US-20260098036-A1 2-HETEROARYL-3-OXO-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES FOR THE TREATMENT OF CANCER DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2026-04-09 US disclosed
EP-4713096-A1 CDK INHIBITOR COMPOUNDS Aleksia Therapeutics, Inc. (US) 2026-03-25 EP disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-12577228-B2 Dihydrocyclopenta-isoquinoline-sulfonamide derivatives compounds UCB Biopharma SRL (BE) 2026-03-17 US disclosed
EP-4692076-A1 HIV INHIBITOR COMPOUNDS Gilead Sciences, Inc. (US) 2026-02-11 EP disclosed
EP-4081296-B1 DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS UCB Biopharma SRL (BE) 2026-02-11 EP disclosed
US-12522594-B2 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2026-01-13 US disclosed
US-12509439-B2 Anti-malarial agents UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2025-12-30 US disclosed
EP-4655069-A1 PYRIDAZINES AS SARM1 INHIBITORS Disarm Therapeutics, Inc. (US) 2025-12-03 EP disclosed
CN-101163678-A Pyridylmethylsulfone derivative DAIICHI SANKYO CO LTD (JP) 2008-04-16 CN disclosed
EP-1892241-A1 NOVEL PIPERIDINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2008-02-27 EP disclosed
EP-1867636-A1 PYRIDYLMETHYLSULFONE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2007-12-19 EP disclosed
US-20070203191-A1 Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines CORTEVA AGRISCIENCE LLC 2007-08-30 US disclosed
US-20070203191-A1 Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines CORTEVA AGRISCIENCE LLC 2007-08-30 US disclosed
US-20070203191-A1 Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines CORTEVA AGRISCIENCE LLC 2007-08-30 US disclosed
WO-2007095229-A2 INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2007-08-23 WO disclosed
WO-2007095229-A2 INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2007-08-23 WO disclosed
CN-1835950-A Imidazopyridine derivatives BANYU PHARMA CO LTD (JP) 2006-09-20 CN disclosed
EP-1657242-A1 IMIDAZOPYRIDINE DERIVATIVES Banyu Pharmaceutical Co., Ltd. (JP) 2006-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098036-A1 2-HETEROARYL-3-OXO-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES FOR THE TREATMENT OF CANCER AHR, CBR1, CNR1 KDM4E 1046/4885ALDH1A1 618/4885S1PR3 908/4885
US-12509439-B2 Anti-malarial agents RCC1, PFN1, NHERF1 KDM4E 3704/4885ALDH1A1 1353/4885S1PR3 1448/4885
US-12577228-B2 Dihydrocyclopenta-isoquinoline-sulfonamide derivatives compounds FCGR2A, FCER2, FCGR1A KDM4E 2965/4885ALDH1A1 2200/4885S1PR3 135/4885
US-20070203191-A1 Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines NPEPPS, PRDX6, HDHD5 KDM4E 1486/4885ALDH1A1 2432/4885S1PR3 567/4885
US-20260132139-A1 HIV INHIBITOR COMPOUNDS SLC11A2, SLC6A15, NHERF1 KDM4E 1200/4885ALDH1A1 2353/4885S1PR3 1577/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 KDM4E 4822/4885ALDH1A1 100/4885S1PR3 505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.