SCHEMBL15613624

SCHEMBL15613624

Cc1nc(CO)cn1COCCSC(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.33
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16886120 0.80 NOTUM (0.37) NOTUMP2RX7
SCHEMBL15613623 0.77
SCHEMBL7447421 0.77 DGAT1 (0.40) NOTUMP2RX7
SCHEMBL17253192 0.66 PTGS2 (0.30)
SCHEMBL14355778 0.66 TYMP (0.45)
SCHEMBL23714049 0.63 DGAT1 (0.40)
SCHEMBL17129283 0.62 PRMT5 (0.32)
SCHEMBL23701940 0.62 DGAT1 (0.37)
Hydrochloric Acid SCHEMBL7440452 0.62 DGAT1 (0.39)
SCHEMBL2552291 0.62 DGAT1 (0.42) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013177668-A1 PROTEIN KINASE INHIBITORS PHARMASCIENCE, INC. (CA) 2013-12-05 WO disclosed