SCHEMBL15616841

SCHEMBL15616841

CCS(=O)(=O)c1cc(C(F)(F)F)ccc1-c1nc2cc(C(F)(F)F)ccc2o1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGPAT2 O15120 2/20 0.47
UTRN P46939 5/20 0.45
PTPN2 P17706 4/20 0.44
PTPN1 P18031 4/20 0.44
PTPN5 P54829 4/20 0.44
HSPD1 P10809 2/20 0.44
HSPE1 P61604 2/20 0.44
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
HDAC6 Q9UBN7 2/20 0.42
CYP1A2 P05177 1/20 0.42
AHR P35869 1/20 0.42
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
CETP P11597 1/20 0.41
PPARG P37231 1/20 0.41
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16746512 0.93 P2RY14 (0.46) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL9951989 0.91 UTRN (0.49) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL1023895 0.88 AGPAT2 (0.44) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL29814188 0.84 AGPAT2 (0.41) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL20633528 0.84 AGPAT2 (0.41) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL16594349 0.81 UTRN (0.42) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL17733125 0.81 UTRN (0.42) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL16375381 0.81 UTRN (0.44) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL16804778 0.81 ALDH1A1 (0.48) AGPAT2UTRNPTPN2PTPN1PTPN5
SCHEMBL15933541 0.81 UTRN (0.42) AGPAT2UTRNPTPN2PTPN1PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150148308-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-28 US disclosed
US-20150148308-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-28 US disclosed
EP-2865266-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS Sumitomo Chemical Company, Limited (JP) 2015-04-29 EP disclosed
WO-2013187426-A1 PEST CONTROL METHOD FOR HARMFUL ARTHROPODS 住友化学株式会社 (JP) 2013-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148308-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS SFXN1, OSR1, PIR AGPAT2 2447/4885UTRN 2585/4885PTPN2 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.