Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17986607 | 0.98 | ADRA2A (0.34) | ADRA2AADRA2BADRA2CTSHRHTR2A | |
| SCHEMBL338410 | 0.98 | ADRA2A (0.34) | ADRA2AADRA2BADRA2CTSHRHTR2A | |
| SCHEMBL569626 | 0.95 | — | — | |
| SCHEMBL4986870 | 0.77 | HTR2C (0.41) | HTR2AHTR2C | |
| SCHEMBL1827327 | 0.71 | PDK1 (0.30) | — | |
| SCHEMBL223932 | 0.71 | PNMT (0.41) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL1834181 | 0.69 | — | — | |
| SCHEMBL21591664 | 0.69 | MAOA (0.46) | ADRA2A | |
| SCHEMBL20723049 | 0.69 | PLAU (0.44) | — | |
| SCHEMBL1834182 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6531 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344342-A | Substituted polyaromatic ring derivatives, compositions and uses thereof | 康迈迪森(北京)医药科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118324816-A | Organometallic compound, light-emitting device, electronic apparatus, and electronic device | 三星显示有限公司 | 2024-07-12 | — | — | CN | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| CN-117917420-A | Organometallic compound, light-emitting device, electronic apparatus, and electronic device | 三星显示有限公司 | 2024-04-23 | — | — | CN | claimed |
| EP-4353262-A1 | NOVEL COMPOUND HAVING INHIBITORY ACTIVITY AGAINST PENDRIN, AND PHARMACEUTICAL USES THEREOF | UIF (University Industry Foundation), Yonsei University (KR) | 2024-04-17 | — | — | EP | claimed |
| CN-117529202-A | Organometallic compound, light-emitting device, electronic apparatus, and electronic device | 三星显示有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117135987-A | Organometallic compound, light-emitting device including the same, electronic device, and electronic device | 三星显示有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-109411632-B | Organic light emitting device and apparatus including the same | 三星显示有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-117062455-A | Organic light emitting device and electronic apparatus including the same | 三星显示有限公司 | 2023-11-14 | — | — | CN | claimed |
| US-20230278958-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-09-07 | — | — | US | claimed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | claimed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | claimed |
| US-4639519-A | 2-substituted alkylaminopyrimidones useful as H2 -antagonists and antiinflamatory agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-01-27 | — | — | US | claimed |
| US-4558128-A | ANTIHISTAMINE, ANTIINFLAMMATORY AGENT | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-12-10 | — | — | US | claimed |
| US-4523015-A | Process and nitroaminopyrimidone intermediates for histamine H2 -antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-11 | — | — | US | claimed |
| US-4496567-A | HSITAMINE H2 ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-01-29 | — | — | US | claimed |
| EP-0013071-B1 | PYRIMIDINONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-11-16 | — | — | EP | claimed |
| US-4305945-A | Isoureas and isothioureas | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-12-15 | — | — | US | claimed |
| EP-0003677-B1 | PYRIMIDONES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-11-11 | — | — | EP | claimed |
| EP-0003677-A2 | Pyrimidones, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-08-22 | — | — | EP | claimed |