Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.75 |
| ▸ | HPGD | P15428 | 6/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | CA12 | O43570 | 1/20 | 0.75 |
| ▸ | CA1 | P00915 | 1/20 | 0.75 |
| ▸ | CA2 | P00918 | 1/20 | 0.75 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.75 |
| ▸ | CA4 | P22748 | 1/20 | 0.75 |
| ▸ | CA6 | P23280 | 1/20 | 0.75 |
| ▸ | CA7 | P43166 | 1/20 | 0.75 |
| ▸ | CA9 | Q16790 | 1/20 | 0.75 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.75 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL1003308 | 0.98 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL4907211 | 0.96 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1829341 | 0.91 | ALDH1A1 (0.82) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL8621859 | 0.90 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL294304 | 0.90 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL25288775 | 0.89 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL31332109 | 0.89 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL28438953 | 0.89 | ALDH1A1 (0.95) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL5183939 | 0.89 | ALDH1A1 (0.95) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL27817575 | 0.89 | ALDH1A1 (0.95) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383835-A1 | A METHOD FOR RECOVERING AN AROMATIC ALCOHOL FROM A MELT POLYMERIZATION, AND A SYSTEM FOR RECOVERING THE SAME | SABIC Global Technologies B.V. (NL) | 2018-10-10 | — | — | EP | disclosed |
| US-9765012-B2 | Method for producing diaryl carbonate | COVESTRO DEUTSCHLAND AG (DE) | 2017-09-19 | — | — | US | disclosed |
| EP-3215551-A1 | METHOD FOR MAKING POLYCARBONATE USING A LIQUID KETONE MIXTURE | SABIC Global Technologies B.V. (NL) | 2017-09-13 | — | — | EP | disclosed |
| WO-2017093974-A1 | A METHOD FOR RECOVERING AN AROMATIC ALCOHOL FROM A MELT POLYMERIZATION, AND A SYSTEM FOR RECOVERING THE SAME | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-08 | — | — | WO | disclosed |
| WO-2016071815-A1 | METHOD FOR MAKING POLYCARBONATE USING A LIQUID KETONE MIXTURE | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-05-12 | — | — | WO | disclosed |
| EP-2970096-A2 | PROCESS FOR PURIFICATION OF DIPHENYL CARBONATE FOR THE MANUFACTURING OF HIGH QUALITY POLYCARBONATE | SABIC Global Technologies B.V. (NL) | 2016-01-20 | — | — | EP | disclosed |
| US-20160002143-A1 | METHOD FOR PRODUCING DIARYL CARBONATE | BAYER MATERIALSCIENCE AG (DE) | 2016-01-07 | — | — | US | disclosed |
| WO-2014141107-A2 | PROCESS FOR PURIFICATION OF DIPHENYL CARBONATE FOR THE MANUFACTURING OF HIGH QUALITY POLYCARBONATE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014141108-A1 | PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014045086-A1 | PROCESS FOR THE CONTINUOUS MANUFACTURE OF ARYL ALKYL CARBONATE AND/OR DIARYL CARBONATE USING VAPOR RECOMPRESSION | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002143-A1 | METHOD FOR PRODUCING DIARYL CARBONATE | PGLS, ALPG, DPAGT1 | ALDH1A1 4011/4885KDM4E 2057/4885HPGD 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.