SCHEMBL156272

SCHEMBL156272

O=[C]OC1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
GPR3 P46089 2/20 0.37
HTR2A P28223 2/20 0.37
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 2/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19580248 0.77 GPR3 (0.37) POLBGPR3HTR2AHDAC3HDAC4
SCHEMBL895388 0.72 HTR2A (0.38) POLBGPR3HTR2AHDAC3HDAC4
SCHEMBL13327258 0.72 GPR3 (0.44) POLBGPR3HTR2AHDAC3HDAC4
SCHEMBL6805564 0.70 ALDH1A1 (0.46) POLBHTR2ACA1CA2ALDH1A1
SCHEMBL5473773 0.69 HTR2A (0.46) POLBGPR3HTR2AHDAC3HDAC4
SCHEMBL68229 0.69 GPR3 (0.41) POLBGPR3HTR2AHDAC3HDAC4
SCHEMBL10518378 0.69 GPR3 (0.46) POLBGPR3HTR2AHDAC3HDAC4
SCHEMBL29090326 0.69 GPR3 (0.41) POLBGPR3HTR2AHDAC3HDAC4
SCHEMBL2138659 0.69 POLB (0.43) POLBGPR3HTR2AHDAC3HDAC4
SCHEMBL8946826 0.68 POLB (0.36) POLBGPR3HTR2AHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 766 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396173-A1 HERBICIDAL MALONAMIDES CONTAINING A CONDENSED RING SYSTEM BASF SE (DE) 2024-07-10 EP claimed
EP-4396163-A1 HERBICIDAL MALONAMIDES CONTAINING MONOCYCLIC HETEROAROMATIC RINGS BASF SE (DE) 2024-07-10 EP claimed
CN-117881662-A Herbicide malonamide containing monocyclic heteroaromatic ring 巴斯夫欧洲公司 2024-04-12 CN claimed
CN-117881667-A Herbicide malonamides containing a condensed ring system 巴斯夫欧洲公司 2024-04-12 CN claimed
CN-117295727-A Pyridazinones as PARP7 inhibitors 中山优理生物医药有限公司 2023-12-26 CN claimed
WO-2023207710-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2023-11-02 WO claimed
CN-114656391-B Polyhydroxy pyrrolidine compound and preparation method and application thereof 中国科学院化学研究所 2023-10-24 CN claimed
CN-116731124-A Process for the preparation of cyclosporin and intermediates thereof 齐鲁制药有限公司 2023-09-12 CN claimed
CN-115916786-A Manufacture of compounds and compositions for inhibiting SHP2 activity 诺华股份有限公司 2023-04-04 CN claimed
WO-2023031199-A1 HERBICIDAL MALONAMIDES CONTAINING MONOCYCLIC HETEROAROMATIC RINGS BASF SE (DE) 2023-03-09 WO claimed
US-5861413-A BACTERICIDES, MICROBIOCIDES; VETERINARY MEDICINE BAYER AKTIENGESELLSCHAFT (DE) 1999-01-19 US claimed
WO-1998032738-A1 NEW COMPOUNDS WITH HEMOREGULATING EFFECT NYCOMED AUSTRIA GMBH (AT) 1998-07-30 WO claimed
EP-0785197-A2 2-oxo and 2-thio-1,2-dihydroquinolinyl-oxazolidinones BAYER AG (DE) 1997-07-23 EP claimed
US-5486476-A FOR USE IN THE PURIFICATION OF ANTIBODIES BOEHRINGER MANNHEIM GMBH (DE) 1996-01-23 US claimed
US-5449778-A Peptide intermediates WARNER-LAMBERT COMPANY (US) 1995-09-12 US claimed
EP-0637305-A1 NOVEL CYCLIC AMINO ACIDS AND DERIVATIVES THEREOF WARNER-LAMBERT COMPANY (US) 1995-02-08 EP claimed
US-5334506-A Phenoxazines bonded to peptide substrate, cleavable by enzyme; BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1994-08-02 US claimed
US-5264577-A Cyclic amino acids and derivatives thereof WARNER-LAMBERT COMPANY (US) 1993-11-23 US claimed
WO-1993021176-A1 NOVEL CYCLIC AMINO ACIDS AND DERIVATIVES THEREOF WARNER-LAMBERT COMPANY (US) 1993-10-28 WO claimed
US-5097014-A Phenoxazonium chromogens for the color blue BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1992-03-17 US claimed