Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21951947 | 0.74 | HTR2A (0.48) | HTR2ACA1CA2POLBACHE | |
| SCHEMBL156272 | 0.72 | POLB (0.39) | HTR2ACA1CA2POLBACHE | |
| SCHEMBL10447563 | 0.72 | ACHE (0.46) | HTR2ACA1CA2POLBACHE | |
| SCHEMBL5732470 | 0.72 | HTR2A (0.38) | HTR2ACA1CA2POLBACHE | |
| SCHEMBL9396561 | 0.71 | CYP1A2 (0.46) | POLBHDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL5749933 | 0.69 | HTR2A (0.48) | HTR2ACA1CA2ACHEBCHE | |
| SCHEMBL16328281 | 0.69 | POLB (0.50) | HTR2APOLBACHEBCHEHDAC3 | |
| SCHEMBL5745828 | 0.69 | HTR1B (0.44) | HTR2AACHEBCHEGPR3RET | |
| SCHEMBL73176 | 0.68 | HTR2A (0.52) | HTR2ACA1CA2POLBHDAC3 | |
| SCHEMBL16708761 | 0.68 | ALDH1A1 (0.40) | HTR2ACA1CA2POLBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210061893-A1 | Diagnostic Kit | PHOENIX PHARMACEUTICALS, INC. (US) | 2021-03-04 | — | — | US | disclosed |
| US-10836812-B2 | Phoenixin peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2020-11-17 | — | — | US | disclosed |
| EP-2714717-B1 | PHOENIXIN PEPTIDES | PHOENIX PHARMACEUTICALS INC (US) | 2017-07-05 | — | — | EP | disclosed |
| US-20170145083-A1 | Phoenixin Peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-9534045-B2 | Phoenixin peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150322141-A1 | Phoenixin Peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2015-11-12 | — | — | US | disclosed |
| US-9018350-B2 | Phoenixin peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-20140163202-A1 | Phoenixin Peptides | PHOENIX PHARMACEUTICALS, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-8586542-B2 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20130281385-A1 | SMALL MOLECULE APOPTOSIS PROMOTERS | JOYANT PHARMACEUTICALS, INC. | 2013-10-24 | — | — | US | disclosed |
| US-20050203015-A1 | Angiogenesis regulation system | PHOENIX PHARMACEUTICALS, INC. | 2005-09-15 | — | — | US | disclosed |
| US-6835806-B2 | Stable water soluble polypeptides which are potent inhibitors of endothelial cell proliferation and of angiogenesis. | PHOENIX PHARMACEUTICALS, INC. | 2004-12-28 | — | — | US | disclosed |
| US-20020111461-A1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | SOMERS TODD C (US) | 2002-08-15 | — | — | US | disclosed |
| EP-1015479-A4 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| US-20020058620-A1 | Cell growth regulation system | PHOENIX PHARMACEUTICALS, INC. (US) | 2002-05-16 | — | — | US | disclosed |
| EP-0792289-B1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | GENENTECH INC (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-1015479-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0999220-A2 | Low molecular weight peptidomimetic growth hormone secretagogues | Genentech, Inc. (US) | 2000-05-10 | — | — | EP | disclosed |
| US-6034216-A | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH INC. (US) | 2000-03-07 | — | — | US | disclosed |
| WO-1998046631-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281385-A1 | SMALL MOLECULE APOPTOSIS PROMOTERS | BID, BAD, BAX | HTR2A 4241/4885CA1 2899/4885CA2 3945/4885 |
| US-20020111461-A1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | GHSR, GHRHR, IGFBP1 | HTR2A 521/4885CA1 3802/4885CA2 1935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.