SCHEMBL1562783

SCHEMBL1562783

CCC(=O)N/N=C\C1(c2ccc(O)cc2O)C=CC=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALPL P05186 1/20 0.32
POLB P06746 1/20 0.32
ALPI P09923 1/20 0.32
ALPG P10696 1/20 0.32
EIF4H Q15056 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HSP90AB1 P08238 1/20 0.32
KDM4E B2RXH2 7/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 4/20 0.31
HTT P42858 3/20 0.31
HPGD P15428 3/20 0.31
MAPT P10636 2/20 0.31
ALOX12 P18054 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SMN1; SMN2 Q16637 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1562786 1.00 NCOA1 (0.33) NCOA1NCOA3MEN1KMT2AALPL
SCHEMBL1563688 0.88 HPGD (0.47) POLBKDM4EALDH1A1LMNAHTT
SCHEMBL1562771 0.88 HPGD (0.47) POLBKDM4EALDH1A1LMNAHTT
SCHEMBL1562776 0.88 HPGD (0.47) POLBKDM4EALDH1A1LMNAHTT
SCHEMBL6446031 0.85 MEN1 (0.32) MEN1KMT2AALPLPOLBALPI
SCHEMBL1563584 0.85 MEN1 (0.32) MEN1KMT2AALPLPOLBALPI
SCHEMBL1563553 0.82 SIRT1 (0.44) MEN1KMT2APOLBKDM4EHPGD
SCHEMBL1563237 0.80 DNM1 (0.45) MEN1KMT2A
SCHEMBL1563232 0.80 DNM1 (0.45) MEN1KMT2A
SCHEMBL1563598 0.78 ALDH1A1 (0.37) KMT2APOLBL3MBTL1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556351-B2 Rubber composition suitable for use as a cap ply in a tire Bridgestone Americas Tire Operations, Inc. (US) 2017-01-31 US disclosed
US-20160040024-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2016-02-11 US disclosed
US-9163127-B2 Rubber composition suitable for use as a cap ply in a tire BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2015-10-20 US disclosed
US-20140005320-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2014-01-02 US disclosed
EP-1475408-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM BRIDGESTONE CORP (JP) 2011-04-06 EP disclosed
US-20050176858-A1 Rubber composition and pneumatic tire made therefrom BRIDGESTONE CORPORATION 2005-08-11 US disclosed
EP-1184412-B1 Rubber composition and heavy duty pneumetic tire using the rubber composition BRIDGESTONE CORP (JP) 2005-01-12 EP disclosed
US-6822027-B2 MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. BRIDGESTONE CORPORATION (JP) 2004-11-23 US disclosed
EP-1475408-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM Bridgestone Corporation (JP) 2004-11-10 EP disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 US disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 EP disclosed