Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563546 | 1.00 | SIRT1 (0.44) | SIRT1KDM1AMAOAMAOBMEN1 | |
| SCHEMBL1563232 | 0.89 | DNM1 (0.45) | SIRT1KDM1AMAOAMAOBMEN1 | |
| SCHEMBL1563237 | 0.89 | DNM1 (0.45) | SIRT1KDM1AMAOAMAOBMEN1 | |
| SCHEMBL1562738 | 0.82 | KDM4E (0.43) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL1562736 | 0.82 | KDM4E (0.43) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL1563584 | 0.82 | MEN1 (0.32) | MEN1KMT2APOLB | |
| SCHEMBL1562783 | 0.82 | NCOA1 (0.33) | MEN1KMT2AKDM4EHPGDGAA | |
| SCHEMBL1562786 | 0.82 | NCOA1 (0.33) | MEN1KMT2AKDM4EHPGDGAA | |
| SCHEMBL1562771 | 0.77 | HPGD (0.47) | NPC1RAB9AKDM4EHPGDGAA | |
| SCHEMBL1562750 | 0.73 | RAB9A (0.45) | SIRT1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556351-B2 | Rubber composition suitable for use as a cap ply in a tire | Bridgestone Americas Tire Operations, Inc. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20160040024-A1 | RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC | 2016-02-11 | — | — | US | disclosed |
| US-9163127-B2 | Rubber composition suitable for use as a cap ply in a tire | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140005320-A1 | RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2014-01-02 | — | — | US | disclosed |
| EP-1475408-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM | BRIDGESTONE CORP (JP) | 2011-04-06 | — | — | EP | disclosed |
| EP-1083199-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2006-08-02 | — | — | EP | disclosed |
| EP-1184412-B1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | BRIDGESTONE CORP (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6822027-B2 | MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. | BRIDGESTONE CORPORATION (JP) | 2004-11-23 | — | — | US | disclosed |
| EP-1475408-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM | Bridgestone Corporation (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-6506849-B1 | Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity | BRIDGESTONE CORPORATION (JP) | 2003-01-14 | — | — | US | disclosed |
| US-20020049294-A1 | Rubber composition and heavy duty pneumatic tire using the rubber composition | BRIDGESTONE CORPORATION | 2002-04-25 | — | — | US | disclosed |
| EP-1184412-A1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | Bridgestone Corporation (JP) | 2002-03-06 | — | — | EP | disclosed |