Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 16/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15628606 | 1.00 | DPP4 (0.35) | DPP4DPP7ACACB | |
| SCHEMBL15628618 | 0.88 | WDR91 (0.40) | ACACB | |
| SCHEMBL15628617 | 0.88 | WDR91 (0.40) | ACACB | |
| SCHEMBL20026251 | 0.84 | ACACB (0.35) | ACACB | |
| SCHEMBL19937334 | 0.83 | DPP4 (0.44) | DPP4DPP7 | |
| SCHEMBL15628607 | 0.82 | ALDH1A1 (0.38) | DPP4DPP7 | |
| SCHEMBL15628457 | 0.81 | ALDH1A1 (0.40) | DPP4DPP7 | |
| SCHEMBL20026360 | 0.81 | ACACB (0.30) | ACACB | |
| SCHEMBL14023911 | 0.80 | ALDH1A1 (0.41) | — | |
| SCHEMBL19062581 | 0.80 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006189-B2 | Triazole compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20140088031-A1 | Triazole Compounds and Methods of Making and Using the Same | RIB-X PHARMACEUTICALS, INC. (US) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088031-A1 | Triazole Compounds and Methods of Making and Using the Same | IL33, PROKR1, VIP | DPP4 229/4885DPP7 175/4885ACACB 3008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.