Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 17/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14023963 | 0.83 | DPP4 (0.37) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL15628606 | 0.83 | DPP4 (0.35) | DPP4DPP7 | |
| SCHEMBL15628549 | 0.83 | DPP4 (0.35) | DPP4DPP7 | |
| SCHEMBL25016625 | 0.79 | HRH3 (0.45) | DPP4DPP7 | |
| SCHEMBL25017269 | 0.79 | HRH3 (0.45) | DPP4DPP7 | |
| SCHEMBL14023952 | 0.74 | DPP4 (0.36) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL14023957 | 0.74 | DPP4 (0.36) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL19937529 | 0.72 | USP2 (0.37) | DPP4 | |
| SCHEMBL20026251 | 0.71 | ACACB (0.35) | — | |
| SCHEMBL19937463 | 0.70 | DPP4 (0.38) | DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290427-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | Melinta Therapeutics, Inc. (US) | 2018-03-07 | — | — | EP | disclosed |