Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17252235 | 0.84 | KMT2A (0.44) | MAPTSMN1; SMN2L3MBTL1HCAR3KMT2A | |
| SCHEMBL10066762 | 0.82 | MAPT (0.44) | MAPTSMN1; SMN2L3MBTL1HCAR3MEN1 | |
| SCHEMBL6205934 | 0.80 | MAPK1 (0.57) | MAPTL3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL17682295 | 0.79 | MAPT (0.42) | MAPTSMN1; SMN2L3MBTL1HCAR3MEN1 | |
| SCHEMBL21316613 | 0.79 | MAPT (0.42) | MAPTSMN1; SMN2L3MBTL1HCAR3MEN1 | |
| SCHEMBL28829391 | 0.77 | MAPT (0.40) | MAPTSMN1; SMN2L3MBTL1HCAR3MEN1 | |
| SCHEMBL28006758 | 0.77 | MAPT (0.40) | MAPTSMN1; SMN2L3MBTL1HCAR3MEN1 | |
| SCHEMBL21574752 | 0.75 | MAPT (0.39) | MAPTSMN1; SMN2L3MBTL1HCAR3MEN1 | |
| SCHEMBL14075263 | 0.73 | POLB (0.41) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL2632670 | 0.73 | HDAC1 (0.56) | MAPTSMN1; SMN2L3MBTL1HCAR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014047024-A1 | IAP ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-03-27 | — | — | WO | disclosed |