Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682295 | 0.86 | MAPT (0.42) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL10066762 | 0.82 | MAPT (0.44) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL27191301 | 0.81 | P4HA1 (0.52) | MAPTL3MBTL1HCAR3HPGD | |
| SCHEMBL21316613 | 0.79 | MAPT (0.42) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL7419600 | 0.79 | MAPK1 (0.56) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| SCHEMBL15630423 | 0.77 | MAPT (0.40) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL28006758 | 0.77 | MAPT (0.40) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL18397143 | 0.76 | GSK3B (0.48) | MAPTL3MBTL1HCAR3RAB9AGSK3B | |
| SCHEMBL21574752 | 0.75 | MAPT (0.39) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL567789 | 0.75 | MAPT (0.44) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566324-A | Hydroxyl purine compound and application thereof | GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD | 2016-05-11 | — | — | CN | disclosed |