SCHEMBL15630907

SCHEMBL15630907

c1cncc(-n2c3ccccc3c3c2c2c4ccccc4n(-c4cccnc4)c2c2c4ccccc4n(-c4cccnc4)c32)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX12 P18054 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.42
▸ ATM Q13315 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ CYP1A2 P05177 3/20 0.42
▸ METAP2 P50579 3/20 0.42
▸ HTT P42858 2/20 0.41
▸ MDM2 Q00987 1/20 0.41
▸ GFER P55789 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ CYP2A6 P11509 2/20 0.40
▸ GAA P10253 2/20 0.40
▸ MAPK1 P28482 2/20 0.40
▸ MAPT P10636 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ GSR P00390 1/20 0.39
▸ EP300 Q09472 1/20 0.39
▸ KAT2B Q92831 1/20 0.39
▸ CYP11B2 P19099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17989811 0.91 L3MBTL1 (0.43) ALOX12KDM4EATML3MBTL1CYP1A2
SCHEMBL20845486 0.89 L3MBTL1 (0.47) ALOX12KDM4EATML3MBTL1CYP1A2
SCHEMBL16484319 0.85 KDM4E (0.59) ALOX12KDM4EATML3MBTL1CYP1A2
SCHEMBL16275567 0.84 ALOX12 (0.38) ALOX12KDM4EATML3MBTL1CYP1A2
SCHEMBL16275559 0.84 ALDH1A1 (0.38) ALOX12KDM4EATML3MBTL1CYP1A2
SCHEMBL16275480 0.84 ALDH1A1 (0.38) ALOX12KDM4EATML3MBTL1CYP1A2
SCHEMBL16275552 0.84 ALOX12 (0.38) ALOX12KDM4EATML3MBTL1CYP1A2
SCHEMBL18057772 0.84 L3MBTL1 (0.42) ALOX12KDM4EATML3MBTL1CYP1A2
SCHEMBL19359918 0.83 L3MBTL1 (0.53) ALOX12KDM4EATML3MBTL1CYP1A2
SCHEMBL17989838 0.83 L3MBTL1 (0.53) ALOX12KDM4EATML3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439150-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-10-08 — — US disclosed
US-20170125705-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-04 — — US disclosed
US-20170125705-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-04 — — US disclosed
US-9502666-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-22 — — US disclosed
US-9502666-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-22 — — US disclosed
US-20140084273-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-27 — — US disclosed
US-20140084273-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439150-B2 Light-emitting element, light-emitting device, electronic device, and lighting device HPRT1, ESR1, PPOX ALOX12 41/4885KDM4E 4212/4885ATM 4093/4885
US-20170125705-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device HPRT1, ESR1, PPOX ALOX12 41/4885KDM4E 4212/4885ATM 4093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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