SCHEMBL15634985

C=C1[C@H]2CC[C@H]3[C@]4(C)C[C@H](O[C@@H]5O[C@H](CO)[C@@H](OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@H]5OC(=O)CC(C)C)C[C@@H](C(=O)O)[C@H]4CC[C@]3(C2)[C@H]1O.[KH].[KH].[NaH]

nearest known ligand 0.88

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	1/20	0.88

▸	HPSE	Q9Y251	5/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3765566	0.99	MAPT (0.89)	MAPTHPSE
SCHEMBL20456989	0.99	MAPT (0.89)	MAPTHPSE
Potassium Ion SCHEMBL30190052	0.94	MAPT (1.00)	MAPTHPSE
Potassium Ion SCHEMBL29767873	0.94	MAPT (1.00)	MAPTHPSE
Potassium Ion SCHEMBL380009	0.94	MAPT (1.00)	MAPTHPSE
Potassium Ion SCHEMBL28493998	0.94	MAPT (1.00)	MAPTHPSE
Water SCHEMBL6357796	0.93	MAPT (0.99)	MAPTHPSE
SCHEMBL19255997	0.92	MAPT (0.78)	MAPTHPSE
SCHEMBL25014383	0.89	MAPT (0.78)	MAPT
SCHEMBL1612956	0.87	MAPT (0.70)	MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2903586-A2	COMPOSITION	Trigiante, Giuseppe (GB)	2015-08-12	—	—	EP	disclosed
WO-2014053860-A2	COMPOSITION	TRIGIANTE GIUSEPPE (GB)	2014-04-10	—	—	WO	disclosed