Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HPSE | Q9Y251 | 14/20 | 0.32 |
| ▸ | FGF1 | P05230 | 9/20 | 0.32 |
| ▸ | FGF2 | P09038 | 8/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL28493998 | 1.00 | MAPT (1.00) | MAPTHPSEFGF1FGF2 | |
| Potassium Ion SCHEMBL30190052 | 1.00 | MAPT (1.00) | MAPTHPSEFGF1FGF2 | |
| Potassium Ion SCHEMBL380009 | 1.00 | MAPT (1.00) | MAPTHPSEFGF1FGF2 | |
| Water SCHEMBL6357796 | 0.99 | MAPT (0.99) | MAPTHPSEFGF1FGF2 | |
| SCHEMBL20456989 | 0.94 | MAPT (0.89) | MAPTHPSE | |
| SCHEMBL3765566 | 0.94 | MAPT (0.89) | MAPTHPSE | |
| SCHEMBL21046219 | 0.94 | MAPT (0.89) | MAPTHPSE | |
| SCHEMBL15634985 | 0.94 | MAPT (0.88) | MAPTHPSE | |
| SCHEMBL25014383 | 0.87 | MAPT (0.78) | MAPT | |
| SCHEMBL19255997 | 0.87 | MAPT (0.78) | MAPTHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107913194-B | Ultraviolet radiation absorbing polymer composition | 强生消费者公司 | 2022-06-28 | — | — | CN | disclosed |