Potassium Ion

SCHEMBL28493998

C=C1C2CC[C@H]3[C@]4(C)C[C@H](OC5OC(CO)C(OS(=O)(=O)[O-])C(OS(=O)(=O)[O-])C5OC(=O)CC(C)C)C[C@@H](C(=O)O)[C@H]4CC[C@]3(C2)[C@H]1O.[K+].[K+]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1 DHFR GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GART NR3C2 PBP2X PTGS1 PTGS2 VKORC1 bla blaT-3 blaT-4 blaT-5 blaT-6 dacA dacB dacC folA ftsI mrcA mrcB mrdA pbp1a pbp1b pbp2a pbp2b pbp3 pol thyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	1/20	1.00

▸	HPSE	Q9Y251	14/20	0.32

▸	FGF1	P05230	9/20	0.32

▸	FGF2	P09038	8/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Potassium Ion SCHEMBL30190052	1.00	MAPT (1.00)	MAPTHPSEFGF1FGF2
Potassium Ion SCHEMBL380009	1.00	MAPT (1.00)	MAPTHPSEFGF1FGF2
Potassium Ion SCHEMBL29767873	1.00	MAPT (1.00)	MAPTHPSEFGF1FGF2
Water SCHEMBL6357796	0.99	MAPT (0.99)	MAPTHPSEFGF1FGF2
SCHEMBL20456989	0.94	MAPT (0.89)	MAPTHPSE
SCHEMBL3765566	0.94	MAPT (0.89)	MAPTHPSE
SCHEMBL21046219	0.94	MAPT (0.89)	MAPTHPSE
SCHEMBL15634985	0.94	MAPT (0.88)	MAPTHPSE
SCHEMBL25014383	0.87	MAPT (0.78)	MAPT
SCHEMBL19255997	0.87	MAPT (0.78)	MAPTHPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-112022864-A	Application of atractyloside in preparation of medicine for treating fatty liver	深圳市龙华区中心医院	2020-12-04	—	—	CN	disclosed