Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HPSE | Q9Y251 | 14/20 | 0.32 |
| ▸ | FGF1 | P05230 | 9/20 | 0.32 |
| ▸ | FGF2 | P09038 | 8/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL30190052 | 1.00 | MAPT (1.00) | MAPTHPSEFGF1FGF2 | |
| Potassium Ion SCHEMBL28493998 | 1.00 | MAPT (1.00) | MAPTHPSEFGF1FGF2 | |
| Potassium Ion SCHEMBL29767873 | 1.00 | MAPT (1.00) | MAPTHPSEFGF1FGF2 | |
| Water SCHEMBL6357796 | 0.99 | MAPT (0.99) | MAPTHPSEFGF1FGF2 | |
| SCHEMBL3765566 | 0.94 | MAPT (0.89) | MAPTHPSE | |
| SCHEMBL20456989 | 0.94 | MAPT (0.89) | MAPTHPSE | |
| SCHEMBL21046219 | 0.94 | MAPT (0.89) | MAPTHPSE | |
| SCHEMBL15634985 | 0.94 | MAPT (0.88) | MAPTHPSE | |
| SCHEMBL25014383 | 0.87 | MAPT (0.78) | MAPT | |
| SCHEMBL19255997 | 0.87 | MAPT (0.78) | MAPTHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 835 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504901-A | Coffee atractyloside with hypoglycemic activity, and preparation method and application thereof | 中国科学院昆明植物研究所 | 2025-02-25 | — | — | CN | claimed |
| CN-115639297-B | Fingerprint construction, identification and detection method of fructus xanthil and fried fructus xanthil traditional Chinese medicine formula particles | 广东一方制药有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-114199818-B | Construction method of near infrared quantitative detection model of fructus xanthil traditional Chinese medicine formula particles and quantitative detection method thereof | 广东一方制药有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-114469967-B | Application of atractyloside A and derivatives thereof in preparation of anxiolytic and antidepressant drugs | 江西中医药大学 | 2024-02-20 | — | — | CN | claimed |
| US-11819535-B2 | Composition and methods for regulating extracellular matrix accumulation | UNIVERSITY HEALTH NETWORK (CA) | 2023-11-21 | — | — | US | claimed |
| CN-115184491-B | Method for measuring chemical component content in qing Jin Yi gas granule | 天津中医药大学 | 2023-08-01 | — | — | CN | claimed |
| CN-115639297-A | Fingerprint construction, identification and detection method of fructus xanthil and fried fructus xanthil traditional Chinese medicine formula particles | 广东一方制药有限公司 | 2023-01-24 | — | — | CN | claimed |
| CN-114624349-B | Method for analyzing traditional Chinese medicinal materials in lung-heat clearing and toxin expelling decoction formula | 中国科学院大连化学物理研究所 | 2022-12-27 | — | — | CN | claimed |
| CN-115364144-A | Yuqing lobular Kuding tea extract and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2022-11-22 | — | — | CN | claimed |
| CN-115184491-A | Method for measuring chemical component content in Qingjin Yiqi granules | 天津中医药大学 | 2022-10-14 | — | — | CN | claimed |
| WO-2000026370-A9 | ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF | MITOKOR (US) | 2001-11-15 | — | — | WO | claimed |
| EP-1116027-A1 | IDENTIFYING AGENTS THAT ALTER MITOCHONDRIAL PERMEABILITY TRANSITION PORES | MITOKOR (US) | 2001-07-18 | — | — | EP | claimed |
| WO-2001032876-A2 | COMPOSITIONS AND METHODS FOR DETERMINING INTERACTIONS OF MITOCHONDRIAL COMPONENTS, AND FOR IDENTIFYING AGENTS THAT ALTER SUCH INTERACTIONS | MITOKOR (US) | 2001-05-10 | — | — | WO | claimed |
| WO-2001016373-A2 | ASSAYING OF MITOCHONDRIAL INTERMEMBRANE SPACE PROTEIN TRANSLOCATION | MITOKOR (US) | 2001-03-08 | — | — | WO | claimed |
| WO-2000079274-A2 | METHODS FOR ASSAYING SUBCELLULAR CONDITIONS USING ENERGY TRANSFER | MITOKOR (US) | 2000-12-28 | — | — | WO | claimed |
| EP-1049780-A1 | ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF | MITOKOR (US) | 2000-11-08 | — | — | EP | claimed |
| WO-2000019200-A9 | IDENTIFYING AGENTS THAT ALTER MITOCHONDRIAL PERMEABILITY TRANSITION PORES | MITOKOR (US) | 2000-08-31 | — | — | WO | claimed |
| WO-2000026370-A2 | ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF | MITOKOR (US) | 2000-05-11 | — | — | WO | claimed |
| WO-2000019200-A1 | IDENTIFYING AGENTS THAT ALTER MITOCHONDRIAL PERMEABILITY TRANSITION PORES | MITOKOR (US) | 2000-04-06 | — | — | WO | claimed |
| WO-1999006588-A1 | A CELL-FREE SYSTEM OF MITOCHONDRIA-DEPENDENT APOPTOSIS, AND METHODS OF USE THEREOF | THE BURNHAM INSTITUTE (US) | 1999-02-11 | — | — | WO | claimed |