Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765566 | 0.93 | MAPT (0.89) | MAPTHPSE | |
| SCHEMBL20456989 | 0.93 | MAPT (0.89) | MAPTHPSE | |
| SCHEMBL15634985 | 0.92 | MAPT (0.88) | MAPTHPSE | |
| Potassium Ion SCHEMBL30190052 | 0.87 | MAPT (1.00) | MAPTHPSE | |
| Potassium Ion SCHEMBL380009 | 0.87 | MAPT (1.00) | MAPTHPSE | |
| Potassium Ion SCHEMBL28493998 | 0.87 | MAPT (1.00) | MAPTHPSE | |
| Potassium Ion SCHEMBL29767873 | 0.87 | MAPT (1.00) | MAPTHPSE | |
| Water SCHEMBL6357796 | 0.87 | MAPT (0.99) | MAPTHPSE | |
| SCHEMBL19248228 | 0.83 | MAPT (0.71) | MAPTHPSE | |
| SCHEMBL25014383 | 0.81 | MAPT (0.78) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170232007-A1 | METHODS AND COMPOSITIONS FOR TREATING ALCOHOL USE DISORDERS | SANNA PIETRO PAOLO (US) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170232007-A1 | METHODS AND COMPOSITIONS FOR TREATING ALCOHOL USE DISORDERS | HSD3B1, HSD11B1, HSD3B2 | MAPT 4186/4885HPSE 449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.