Sugi Predict

Sugi Predict / Compounds / SCHEMBL156355

SCHEMBL156355

SCHEMBL156355

Nc1ccc(N2CCCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 11/20 0.95
▸ MAPT P10636 9/20 0.95
▸ GAA P10253 4/20 0.95
▸ KDM4E B2RXH2 4/20 0.95
▸ L3MBTL1 Q9Y468 4/20 0.95
▸ HTT P42858 3/20 0.95
▸ KMT2A Q03164 3/20 0.95
▸ ALOX15 P16050 3/20 0.95
▸ MEN1 O00255 2/20 0.95
▸ POLB P06746 2/20 0.95
▸ NPC1 O15118 1/20 0.95
▸ USP2 O75604 1/20 0.95
▸ TP53 P04637 1/20 0.95
▸ THRB P10828 1/20 0.95
▸ RECQL P46063 1/20 0.95
▸ RAB9A P51151 1/20 0.95
▸ NPSR1 Q6W5P4 1/20 0.95
▸ HSD17B10 Q99714 1/20 0.95
▸ LMNA P02545 5/20 0.61
▸ GFER P55789 4/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6608042 1.00 ALDH1A1 (0.95) ALDH1A1MAPTGAAKDM4EL3MBTL1
SCHEMBL1986101 1.00 ALDH1A1 (0.95) ALDH1A1MAPTGAAKDM4EL3MBTL1
Hydrochloric Acid SCHEMBL9014036 0.98 ALDH1A1 (1.00) ALDH1A1MAPTGAAKDM4EL3MBTL1
SCHEMBL33852 0.97 ALDH1A1 (0.91) ALDH1A1MAPTGAAKDM4EL3MBTL1
Hydrochloric Acid SCHEMBL1153999 0.95 ALDH1A1 (0.95) ALDH1A1MAPTGAAKDM4EL3MBTL1
SCHEMBL7130594 0.93 ALDH1A1 (0.83) ALDH1A1MAPTGAAKDM4EL3MBTL1
SCHEMBL1858354 0.92 ALDH1A1 (0.82) ALDH1A1MAPTGAAKDM4EL3MBTL1
SCHEMBL7128309 0.91 ALDH1A1 (0.79) ALDH1A1MAPTGAAKDM4EL3MBTL1
SCHEMBL112440 0.90 MAPT (0.78) ALDH1A1MAPTGAAKDM4EL3MBTL1
Hydrochloric Acid SCHEMBL5169602 0.88 MAPT (0.83) ALDH1A1MAPTGAAKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349749-B Synthesis method of apixaban 南京正科医药股份有限公司 2023-11-10 — — CN claimed
CN-113072937-B Lipid drop targeted carbon dot, preparation method and application 郑州大学 2022-06-07 — — CN claimed
CN-114349749-A Synthesis method of apixaban 南京正科医药股份有限公司 2022-04-15 — — CN claimed
CN-109678788-B 1, 2-diaryl indole, derivative and synthetic method thereof 湘潭大学 2021-05-04 — — CN claimed
CN-109678788-A A kind of 1,2- diaryl indoles, derivative and its synthetic method 湘潭大学 2019-04-26 — — CN claimed
CN-106619701-A Western medicine composition for treating coronary heart disease and preparation method thereof 郑州郑先医药科技有限公司 2017-05-10 — — CN claimed
EP-2611797-B1 QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS HANMI SCIENCE CO LTD (KR) 2016-12-28 — — EP claimed
US-8835458-B2 Quinoline or quinazoline derivatives with apoptosis inducing activity on cells HANMI SCIENCE CO., LTD (KR) 2014-09-16 — — US claimed
US-20140200354-A1 Process for the Manufacture of Non-Steroidal Anti-Inflammatory Agents and Intermediates Thereof INTENDIS GMBH (DE) 2014-07-17 — — US claimed
CN-101679247-B Process for preparing non-steroidal anti-inflammatory drugs and intermediates thereof INTENDIS GMBH 2014-02-19 — — CN claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 — — US claimed
US-4865618-A New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said L'OREAL (FR) 1989-09-12 — — US claimed
US-4865617-A Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers L'OREAL (FR) 1989-09-12 — — US claimed
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 — — EP claimed
EP-0294669-A1 Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair L'OREAL (FR) 1988-12-14 — — EP claimed
US-4692166-A OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE L'OREAL (FR) 1987-09-08 — — US claimed
US-4337061-A NITRO DYES IN AQUEOUS SOLUTION SOCIETE ANONYME DITE: L'OREAL (FR) 1982-06-29 — — US claimed
US-4200432-A HAIR DYES L'OREAL (FR) 1980-04-29 — — US claimed
US-3961879-A P-PHENYLENEDIAMINE, HAIR L'OREAL (FR) 1976-06-08 — — US claimed
US-3948596-A Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler SOCIETE ANONYME DITE: L'OREAL (FR) 1976-04-06 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140200354-A1 Process for the Manufacture of Non-Steroidal Anti-Inflammatory Agents and Intermediates Thereof CYP2F1, CYP4A11, CYP11B1 ALDH1A1 1720/4885MAPT 4769/4885GAA 3767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.