Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.95 |
| ▸ | MAPT | P10636 | 9/20 | 0.95 |
| ▸ | GAA | P10253 | 4/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.95 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.95 |
| ▸ | HTT | P42858 | 3/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.95 |
| ▸ | MEN1 | O00255 | 2/20 | 0.95 |
| ▸ | POLB | P06746 | 2/20 | 0.95 |
| ▸ | NPC1 | O15118 | 1/20 | 0.95 |
| ▸ | USP2 | O75604 | 1/20 | 0.95 |
| ▸ | TP53 | P04637 | 1/20 | 0.95 |
| ▸ | THRB | P10828 | 1/20 | 0.95 |
| ▸ | RECQL | P46063 | 1/20 | 0.95 |
| ▸ | RAB9A | P51151 | 1/20 | 0.95 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.95 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.95 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | GFER | P55789 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608042 | 1.00 | ALDH1A1 (0.95) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL156355 | 1.00 | ALDH1A1 (0.95) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9014036 | 0.98 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL33852 | 0.97 | ALDH1A1 (0.91) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1153999 | 0.95 | ALDH1A1 (0.95) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL7130594 | 0.93 | ALDH1A1 (0.83) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL1858354 | 0.92 | ALDH1A1 (0.82) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL7128309 | 0.91 | ALDH1A1 (0.79) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL112440 | 0.90 | MAPT (0.78) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5169602 | 0.88 | MAPT (0.83) | ALDH1A1MAPTGAAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453477-B1 | DEVELOPER-COUPLER COMBINATION CONTAINING 2,4-DICHLORO-3-AMINOPHENOL | HENKEL KGAA (DE) | 2007-10-17 | — | — | EP | claimed |
| JP-2007523865-A | — | — | 2007-08-23 | — | — | JP | claimed |
| US-7129235-B2 | Amides useful for treating pain | ABBOTT LABORATORIES (US) | 2006-10-31 | — | — | US | claimed |
| EP-1646621-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | Abbott Laboratories (US) | 2006-04-19 | — | — | EP | claimed |
| US-20050080095-A1 | administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I | ABBVIE INC. | 2005-04-14 | — | — | US | claimed |
| EP-1512684-A1 | use of derivative of para-phenylenediamine substituted by a homopiperidine ring, for the dyeing of keratinous fibres | L'OREAL (FR) | 2005-03-09 | — | — | EP | claimed |
| WO-2005007642-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | ABBOTT LABORATORIES (US) | 2005-01-27 | — | — | WO | claimed |
| CN-115151252-B | Iron death inhibitor-diarylamine acetamides | 维泰瑞隆有限公司 | 2024-08-27 | — | — | CN | disclosed |
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |
| US-20230159492-A1 | FERROPTOSIS INHIBITORS - DIARYLAMINE PARA-ACETAMIDES | Sironax Ltd. (KY) | 2023-05-25 | — | — | US | disclosed |
| US-20230159492-A1 | FERROPTOSIS INHIBITORS - DIARYLAMINE PARA-ACETAMIDES | Sironax Ltd. (KY) | 2023-05-25 | — | — | US | disclosed |
| US-20230159492-A1 | FERROPTOSIS INHIBITORS - DIARYLAMINE PARA-ACETAMIDES | Sironax Ltd. (KY) | 2023-05-25 | — | — | US | disclosed |
| US-20220356176-A1 | Kv11.1-3.1 INHIBITING METHODS AND COMPOSITIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-11-10 | — | — | US | disclosed |
| EP-0459210-B1 | Color developing agent and process for forming image | FUJI PHOTO FILM CO LTD (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5427897-A | Using pyrrolo-triazole derivatives as cyan dye-forming coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5380625-A | N,N-substituted malondiamide couplers and aromatic primary amine color developers | FUJI PHOTO FILM CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5278034-A | Color development agent | FUJI PHOTO FILM CO., LTD. (JP) | 1994-01-11 | — | — | US | disclosed |
| US-5264331-A | Phenylenediamine developers for silver halide emulsion images | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5223380-A | Using a p-phenylenediamine color developing agent | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0459210-A1 | Color developing agent and process for forming image | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356176-A1 | Kv11.1-3.1 INHIBITING METHODS AND COMPOSITIONS | KCNAB1, KCNMA1, KCNA1 | ALDH1A1 1489/4885MAPT 2623/4885GAA 2143/4885 |
| US-20050080095-A1 | administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I | TRPV1, OPRL1, TRPV6 | ALDH1A1 843/4885MAPT 4422/4885GAA 2594/4885 |
| US-20230159492-A1 | FERROPTOSIS INHIBITORS - DIARYLAMINE PARA-ACETAMIDES | AIFM2, FECH, GPX4 | ALDH1A1 395/4885MAPT 4384/4885GAA 4193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.