SCHEMBL112440

SCHEMBL112440

Nc1ccc(N2CCCN(c3ccc(N)cc3)CC2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.78
ALDH1A1 P00352 7/20 0.78
GAA P10253 6/20 0.78
KDM4E B2RXH2 3/20 0.78
HTT P42858 3/20 0.78
KMT2A Q03164 3/20 0.78
L3MBTL1 Q9Y468 3/20 0.78
MEN1 O00255 2/20 0.78
ALOX15 P16050 2/20 0.78
NPC1 O15118 1/20 0.78
USP2 O75604 1/20 0.78
TP53 P04637 1/20 0.78
POLB P06746 1/20 0.78
THRB P10828 1/20 0.78
RECQL P46063 1/20 0.78
RAB9A P51151 1/20 0.78
NPSR1 Q6W5P4 1/20 0.78
HSD17B10 Q99714 1/20 0.78
LMNA P02545 6/20 0.68
GFER P55789 5/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5169602 0.98 MAPT (0.83) MAPTALDH1A1GAAKDM4EHTT
SCHEMBL1858354 0.97 ALDH1A1 (0.82) MAPTALDH1A1GAAKDM4EHTT
SCHEMBL33852 0.92 ALDH1A1 (0.91) MAPTALDH1A1GAAKDM4EHTT
SCHEMBL6151120 0.92 MAPT (0.77) MAPTALDH1A1GAAKDM4EHTT
SCHEMBL7043679 0.92 MAPT (0.77) MAPTALDH1A1GAAKDM4EHTT
SCHEMBL23347931 0.92 MAPT (0.77) MAPTALDH1A1GAAKDM4EHTT
SCHEMBL1986101 0.90 ALDH1A1 (0.95) MAPTALDH1A1GAAKDM4EHTT
SCHEMBL156355 0.90 ALDH1A1 (0.95) MAPTALDH1A1GAAKDM4EHTT
Hydrochloric Acid SCHEMBL1153999 0.90 ALDH1A1 (0.95) MAPTALDH1A1GAAKDM4EHTT
SCHEMBL6608042 0.90 ALDH1A1 (0.95) MAPTALDH1A1GAAKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12178897-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-12-31 US claimed
US-12109291-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-10-08 US claimed
US-12102704-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-10-01 US claimed
US-12097274-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-09-24 US claimed
US-12070517-B2 Thickened alkalyzation component for oxidative hair dyeing product HENKEL AG & CO. KGAA (DE) 2024-08-27 US claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
US-20230338267-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT HENKEL AG & CO. KGAA (DE) 2023-10-26 US claimed
US-20230310296-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations HENKEL AG & CO. KGAA (DE) 2023-10-05 US claimed
WO-2023163903-A1 OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS HENKEL AG & CO. KGAA (DE) 2023-08-31 WO claimed
US-20230270648-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations HENKEL AG & CO. KGAA (DE) 2023-08-31 US claimed
EP-1199065-A2 Hair dye Henkel Kommanditgesellschaft auf Aktien (DE) 2002-04-24 EP claimed
WO-2001097766-A2 OXIDISED HAIR DYE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
WO-2001047483-A1 USE OF METHYLCHINOLINIUM COMPOUNDS FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-07-05 WO claimed
WO-2001041716-A2 COLOURING COMBINATION BASED ON A M-PHENYLENEDIAMINE DERIVATIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-06-14 WO claimed
WO-2001041717-A2 NEW COLOURING COMBINATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-06-14 WO claimed
WO-2001034105-A1 AGENT FOR COLOURING KERATIN CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-05-17 WO claimed
WO-2001034104-A1 COLOURING AGENT FOR KERATIN CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-05-17 WO claimed
US-6165230-A 1,4-diazacycloheptane derivatives and their use in hair oxidation dyes HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-12-26 US claimed
EP-0966449-A1 NOVEL 1,4-DIAZACYCLOHEPTANE DERIVATIVES AND THEIR USE IN HAIR OXIDATION DYES Henkel Kommanditgesellschaft auf Aktien (DE) 1999-12-29 EP claimed
WO-1998038175-A1 NOVEL 1,4-DIAZACYCLOHEPTANE DERIVATIVES AND THEIR USE IN HAIR OXIDATION DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-09-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12109291-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, ALDH2 MAPT 1335/4885ALDH1A1 40/4885GAA 4422/4885
US-20230338267-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT OGG1, ALPG, OAT MAPT 3334/4885ALDH1A1 1913/4885GAA 478/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO MAPT 2879/4885ALDH1A1 111/4885GAA 2405/4885
US-20230270648-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations KRT18, ALDH5A1, ALDH2 MAPT 992/4885ALDH1A1 26/4885GAA 3966/4885
US-12070517-B2 Thickened alkalyzation component for oxidative hair dyeing product OGG1, ALPG, OAT MAPT 2887/4885ALDH1A1 1825/4885GAA 498/4885
US-12102704-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, ALDH2 MAPT 992/4885ALDH1A1 26/4885GAA 3966/4885
US-12097274-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, COX5A MAPT 1359/4885ALDH1A1 28/4885GAA 4289/4885
US-20230310296-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations KRT18, ALDH5A1, ALDH2 MAPT 1335/4885ALDH1A1 40/4885GAA 4422/4885
US-12178897-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, COX5A MAPT 984/4885ALDH1A1 37/4885GAA 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.