Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 4/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636999 | 1.00 | UBE2M (0.42) | UBE2MDCUN1D1OPRM1CHRNB2CHRNB4 | |
| SCHEMBL18686361 | 0.79 | GPR119 (0.43) | — | |
| Dihydrocinnamaldehyde SCHEMBL15636710 | 0.78 | SLC6A4 (0.42) | KCNH2 | |
| SCHEMBL15636742 | 0.76 | SLC6A4 (0.47) | KCNH2 | |
| SCHEMBL15636758 | 0.72 | KDM5B (0.43) | KCNH2 | |
| SCHEMBL15994239 | 0.72 | KDM5B (0.47) | TMEM97 | |
| SCHEMBL15637014 | 0.72 | KDM5B (0.38) | — | |
| SCHEMBL19609230 | 0.71 | KDM1A (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4KCNH2 | |
| SCHEMBL15637001 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL15637029 | 0.70 | KDM5B (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903968-A1 | INHIBITORS OF HISTONE DEMETHYLASES | Epitherapeutics ApS (DK) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014053491-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2014-04-10 | — | — | WO | disclosed |