Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29572130 | 1.00 | NPC1 (0.42) | NPC1RAB9AMGLLMAPTALDH1A1 | |
| SCHEMBL29571825 | 0.78 | ADORA2A (0.43) | MGLLMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL28534253 | 0.78 | POLB (0.40) | NPC1RAB9AMAPTALDH1A1MAPK1 | |
| SCHEMBL15637454 | 0.78 | ADORA2A (0.43) | MGLLMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL11785056 | 0.76 | ALDH1A1 (0.54) | NPC1RAB9AMAPTALDH1A1MAPK1 | |
| SCHEMBL15639322 | 0.74 | MEN1 (0.33) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL18039129 | 0.72 | P2RX7 (0.53) | NPC1RAB9AMAPTALDH1A1MAPK1 | |
| SCHEMBL15639943 | 0.69 | NPC1 (0.38) | NPC1RAB9AMGLLMAPTALDH1A1 | |
| SCHEMBL29572211 | 0.69 | NPC1 (0.38) | NPC1RAB9AMGLLMAPTALDH1A1 | |
| SCHEMBL15639447 | 0.68 | MGLL (0.37) | NPC1RAB9AMGLLMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548854-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2023-01-10 | — | — | US | disclosed |
| US-11332448-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2022-05-17 | — | — | US | disclosed |
| CN-113243374-B | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-113243374-A | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-108477173-B | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2021-07-02 | — | — | CN | disclosed |
| US-10961201-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2021-03-30 | — | — | US | disclosed |
| US-20210053924-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-02-25 | — | — | US | disclosed |
| US-20210017136-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-01-21 | — | — | US | disclosed |
| US-10689348-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2020-06-23 | — | — | US | disclosed |
| US-10435374-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2019-10-08 | — | — | US | disclosed |
| CN-108477173-A | Heterocyclic compound as insecticide | 拜耳农作物科学股份公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-105101800-B | Heterocyclic Compounds as Pesticides | 拜耳农作物科学股份公司 | 2018-04-13 | — | — | CN | disclosed |
| US-9802899-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-10-26 | — | — | US | disclosed |
| EP-2903440-B1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROLLING AGENTS | BAYER CROPSCIENCE AG (DE) | 2017-09-06 | — | — | EP | disclosed |
| CN-105101800-A | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG | 2015-11-25 | — | — | CN | disclosed |
| US-20150239847-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2015-08-27 | — | — | US | disclosed |
| EP-2903440-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | Bayer CropScience AG (DE) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014053450-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435374-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | NPC1 3509/4885RAB9A 1244/4885MGLL 1199/4885 |
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | NPC1 3509/4885RAB9A 1244/4885MGLL 1199/4885 |
| US-10961201-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | NPC1 3509/4885RAB9A 1244/4885MGLL 1199/4885 |
| US-10689348-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | NPC1 3509/4885RAB9A 1244/4885MGLL 1199/4885 |
| US-11548854-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | NPC1 3509/4885RAB9A 1244/4885MGLL 1199/4885 |
| US-20210053924-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | NPC1 3509/4885RAB9A 1244/4885MGLL 1199/4885 |
| US-11332448-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | NPC1 3509/4885RAB9A 1244/4885MGLL 1199/4885 |
| US-20210017136-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | NPC1 3509/4885RAB9A 1244/4885MGLL 1199/4885 |
| US-20150239847-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | NPC1 3509/4885RAB9A 1244/4885MGLL 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.